365428-83-7 Usage
Thiazole and pyridine families
4-(2-ethyl-4-phenyl-1,3-thiazol-5-yl)pyridin-2-amine belongs to these chemical compound families.
Heterocyclic compound
It contains a thiazole ring and a pyridine ring, making it a heterocyclic compound.
Amine functional group
It contains an amine functional group, which is important for its biological activity.
Potential applications in medicinal chemistry
Due to its unique structural features, it could be useful in drug design.
Biological activity and therapeutic uses
Researchers are interested in studying its biological activity and potential therapeutic uses in pharmaceutical development.
Check Digit Verification of cas no
The CAS Registry Mumber 365428-83-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,5,4,2 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 365428-83:
(8*3)+(7*6)+(6*5)+(5*4)+(4*2)+(3*8)+(2*8)+(1*3)=167
167 % 10 = 7
So 365428-83-7 is a valid CAS Registry Number.
365428-83-7Relevant articles and documents
Novel inhibitor of p38 MAP kinase as an anti-TNF-α drug: Discovery of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a potent and orally active anti-rheumatoid arthritis agent
Miwatashi, Seiji,Arikawa, Yasuyoshi,Kotani, Etsuo,Miyamoto, Maki,Naruo, Ken-Ichi,Kimura, Hiroyuki,Tanaka, Toshimasa,Asahi, Satoru,Ohkawa, Shigenori
, p. 5966 - 5979 (2007/10/03)
The p38 mitogen-activated protein (MAP) kinase has been implicated in the proinflammatory cytokine signal pathway, and its inhibitors are potentially useful for the treatment of chronic inflammatory diseases such as rheumatoid arthritis (RA) and inflammat
JNK INHIBITOR
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Page/Page column 92, (2010/02/07)
The present invention relates to a c-Jun N-terminal kinase inhibitor containing an azole compound (I) substituted by a nitrogen-containing aromatic group having substituent(s)(except a compound represented by the formula: ) or a salt thereof or a prodrug thereof.