365572-48-1 Usage
Description
C-(N-tert-butoxycarbonylamino)methanol, also known as N-Boc-aminomethanol, is an organic compound with the molecular formula C5H11NO2. It is a derivative of aminomethanol, featuring a tert-butoxycarbonyl (Boc) protecting group, which is commonly used in organic synthesis to protect amino groups from unwanted reactions. C-(N-tert-butoxycarbonylamino)methanol is characterized by its ability to form stable carbamates and is widely utilized in the pharmaceutical and chemical industries due to its unique reactivity and protective properties.
Uses
Used in Pharmaceutical Industry:
C-(N-tert-butoxycarbonylamino)methanol is used as a synthetic reagent for the preparation of various pharmaceutical compounds. Its primary application is in the synthesis of somatotropin polypeptides, which act as antagonists to prevent the activation of growth hormone receptors. This makes it a valuable compound in the development of drugs targeting growth-related disorders and conditions.
Used in Chemical Synthesis:
In the chemical synthesis industry, C-(N-tert-butoxycarbonylamino)methanol serves as a versatile building block for the creation of a wide range of organic compounds. Its Boc-protected amino group allows for selective reactions, making it an essential component in the synthesis of complex molecules, such as pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Peptide Synthesis:
C-(N-tert-butoxycarbonylamino)methanol is also utilized in the field of peptide synthesis, where it is employed as a protecting group for amino groups during the assembly of peptide chains. The Boc group can be selectively removed when needed, allowing for the controlled stepwise synthesis of peptides and the introduction of specific amino acid residues at desired positions within the peptide sequence.
Check Digit Verification of cas no
The CAS Registry Mumber 365572-48-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,5,5,7 and 2 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 365572-48:
(8*3)+(7*6)+(6*5)+(5*5)+(4*7)+(3*2)+(2*4)+(1*8)=171
171 % 10 = 1
So 365572-48-1 is a valid CAS Registry Number.
365572-48-1Relevant articles and documents
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction
D'Agostino, Ilaria,Giacchello, Ilaria,Nannetti, Giulio,Fallacara, Anna Lucia,Deodato, Davide,Musumeci, Francesca,Grossi, Giancarlo,Palù, Giorgio,Cau, Ylenia,Trist, Iuni Margaret,Loregian, Arianna,Schenone, Silvia,Botta, Maurizio
supporting information, p. 743 - 758 (2018/08/24)
The limited treatment options against influenza virus along with the growing public health concerns regarding the continuous emergence of drug-resistant viruses make essential the development of new anti-flu agents with novel mechanisms of action. One of
Enantioselective organocatalytic intramolecular aza-Michael reaction: A concise synthesis of (+)-sedamine, (+)-allosedamine, and (+)-coniine
Fustero, Santos,Jimenez, Diego,Moscardo, Javier,Catalan, Silvia,Del Pozo, Carlos
, p. 5283 - 5286 (2008/09/18)
(Chemical Equation Presented) The intramolecular aza-Michael reaction of carbamates bearing remote α,β-unsaturated aldehydes under organocatalytic conditions took place with good yields and excellent ee's when Jorgensen catalyst IV was used in the process, giving rise to the enantioselective formation of several five- and six-membered heterocycles. The developed methodology was applied to the synthesis of three piperidine alkaloids.
