366-38-1

Basic information

• Product Name: Morpholine, 4-(fluoroacetyl)- (6CI,8CI,9CI)
• Synonyms: Morpholine, 4-(fluoroacetyl)- (6CI,8CI,9CI)
• CAS NO: 366-38-1
• Molecular Formula: C6H10FNO2
• Molecular Weight: 147.1475032
• Product Categories: ACETYLHALIDE
• Mol File: 366-38-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Morpholine, 4-(fluoroacetyl)- (6CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-(fluoroacetyl)- (6CI,8CI,9CI)(366-38-1)
• EPA Substance Registry System: Morpholine, 4-(fluoroacetyl)- (6CI,8CI,9CI)(366-38-1)

Safety Data

• Hazardous Substances Data: 366-38-1(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 359-06-8 monofluoroacetyl chloride 
• 459-72-3 ethyl 2-fluoroacetate 
• 453-18-9 methyl fluoroacetate 

Downstream Products

• 908253-55-4 1-fluoro-4-(trimethylsilyl)but-3-yn-2-one 

Relevant articles and documents

The observation of a large gauche preference when 2-fluoroethylamine and 2-fluoroethanol become protonated

The energies of the gauche and anti conformers of 2-fluoroethylamine, 2-fluoroethanol and their protonated analogues are calculated using density functional theory. Unlike the non protonated systems, the protonated systems show a strong gauche effect where the C-F and the C-+NH3 or C-F and C-+OH2 bonds are gauche rather than anti to each other. Single crystal X-ray diffraction studies of 2-fluoroethylammonium compounds identify the same conformational preference.

A NOVEL PROCESS FOR PREPARING 3-AMINO-5-FLUORO-4-DIALKOXYPENTANOIC ACID ESTER

The present invention relates to a novel process for the production of 3-amino-5- fluoro-4-dialkoxypentanoic acid ester used in the precursor of 3-amino-5-fluoro-4- oxopentanoic acid, represented by the following formula (I) : wherein R1 and R2 are as def