36635-79-7

Basic information

• Product Name: 2-Propen-1-one, 1-[1,1'-biphenyl]-4-yl-3-(3,4-dimethoxyphenyl)-
• CAS NO: 36635-79-7
• Molecular Formula: C23H20O3
• Molecular Weight: 344.41
• Mol File: 36635-79-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-[1,1'-biphenyl]-4-yl-3-(3,4-dimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-[1,1'-biphenyl]-4-yl-3-(3,4-dimethoxyphenyl)-(36635-79-7)
• EPA Substance Registry System: 2-Propen-1-one, 1-[1,1'-biphenyl]-4-yl-3-(3,4-dimethoxyphenyl)-(36635-79-7)

Safety Data

• Hazardous Substances Data: 36635-79-7(Hazardous Substances Data)

Upstream product

• 92-91-1 biphenyl-4-acetaldehyde 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 98-80-6 phenylboronic acid 
• 99-90-1 para-bromoacetophenone 

Downstream Products

• 1017240-38-8 C₂₃H₂₂N₂O₂ 
• 1417894-77-9 3-(biphenyl-4-yl)-5-(3,4-dimethoxyphenyl)pyrazole 

Relevant articles and documents

Synthesis of diverse novel compounds with anticipated antitumor activities starting with biphenyl chalcone

The chalcone as (E)-1-([1,1′-biphenyl]-4-yl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (3) was reacted with various active methylene compounds via Michael addition reaction under different conditions. In one hand, chalcone 3 reacted with isatin and glycine in one pot reaction via 1,3-dipolar cycloaddition reaction. On the other hand, chalcone 3 was also reacted with different N-nucleophiles via direct addition on the carbonyl group to award cyclic and/or acyclic products. Meanwhile, the reaction of chalcone 3 with S-benzylthiuronium chloride afforded the thio-Michael addition product. Chalcone 3 and 10 novel synthesized compounds were screened against two cell lines (HepG2 and MCF-7). Among of them, thiosemicarbazone 16, oxime 14 and pyrimidine-2(1H)-thione 19 derivatives revealed an excellent activity against both cell lines (IC50 values = 6.79-12.91 μM), whereas thiosemicarbazone 16 (6.79 ± 0.5 and 7.58 ± 0.6 μM) showed the highest activity.

Synthesis of new schiff base of 1,3-oxazine and 1,3-thiazine derivatives derived from 4-phenyl substituted chalcones and evaluation of their antibacterial activity

Oxazine and thiazine heterocycles have distinctive interests due to their important class of natural and non-natural products and exhibit high biological activities in the pharmaceutical and biological fields. This work was planned to synthesize Schiff ba

Solvent free synthesis of different substituted pyrazoles under microwave irradiation via one pot synthesis and their biological evaluation

Pyrazoles and their derivative are widely used as pharmaceutical and agrochemical agents and consequently a large number of synthetic routes to pyrazole have been reported. Due to the property of reducing blood sugar by pyrazole, it has resulted in the sy