36679-40-0Relevant articles and documents
Reactive oxygen species generation and its role in the differential cytotoxicity of the arylhydroxylamine metabolites of sulfamethoxazole and dapsone in normal human epidermal keratinocytes
Vyas, Piyush M.,Roychowdhury, Sanjoy,Woster, Patrick M.,Svensson, Craig K.
, p. 275 - 286 (2005)
Cutaneous drug reactions (CDR) are responsible for numerous minor to life-threatening complications. Though the exact mechanism for CDR is not completely understood, evidence suggests that bioactivation of drugs to reactive oxygen or nitrogen species is a