36685-63-9

Basic information

• Product Name: 3-(2,4-dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one
• CAS NO: 36685-63-9
• Molecular Formula: C₁₇H₁₆O₄
• Molecular Weight: 284.3065
• Mol File: 36685-63-9.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 480.5°C at 760 mmHg
• Flash Point: 177.5°C
• Density: 1.203g/cm³
• Vapor Pressure: 7.43E-10mmHg at 25°C
• Refractive Index: 1.614
• CAS DataBase Reference: 3-(2,4-dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,4-dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one(36685-63-9)
• EPA Substance Registry System: 3-(2,4-dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one(36685-63-9)

Safety Data

• Hazardous Substances Data: 36685-63-9(Hazardous Substances Data)

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Downstream Products

• 63487-16-1 2-(2,4-dimethoxyphenyl)-4H-chromen-4-one 
• 29219-05-4 7,2'-dimethoxyflavonol 
• 98583-84-7 2-(2,4-dimethoxyphenyl)-2,3-dihydro-4H-chromen-4-one 
• 354128-26-0 3-(2-hydroxy-phenyl)-1-(2,4-dimethoxy-phenyl)-propan-1-one 
• 36752-68-8 (Z)-2-(2,4-dimethoxybenzylidene)benzofuran-3(2H)-one 
• 90834-27-8 4-[(E)-2-(2,4-Dimethoxy-phenyl)-vinyl]-chromen-2-one 
• 77298-66-9 7,2'-dihydroxyflavone 
• 170310-00-6 2’,4’-dihydroxyflavone 
• 1108203-72-0 4-(2-hydroxyphenyl)-2-(2,4-dimethoxyphenyl)-2,3-dihydro-1H-1,5-benzodiazepine 
• 206194-42-5 2',4'-Dimethoxy-3-hydroxyflavone 

Relevant articles and documents

Synthesis and antibacterial activity of chalcone derivatives containing thioether triazole

The infection of Xanthomonas oryzae pv. Oryzae (Xoo), Ralstonia solanacearum (Rs), and Xanthomonas axonopodis pv. Citri (Xac) has become a major problem in agricultural production. In this study, a series of novel chalcone derivatives containing thioether triazoles were designed and synthesized. The structures of the novel compounds were systematically characterized via 1H-NMR, 13C-NMR, and HRMS. Moreover, the antibacterial activity results showed that E10, E11, E15, and E16 have adequate antibacterial activities against Xoo, Rs, and Xac. Among the different compounds, E15 exhibited remarkable inhibitory effect against Xac with an EC50 of 9.1 μg.mL-1, which was better than that of commercial agent bismerthiazol (54.9 μg.mL-1). In addition, the possible antibacterial mechanism of the target compound E15 against Xac was studied via scanning electron microscopy (SEM).

1H and 13C NMR spectral assignments of 2′-hydroxychalcones

Chalcones are of interest to medicinal chemists because their structures can be easily modified with various functional groups. The syntheses and biological activities of chalcones from natural sources are well known. In this study, 24 2′-hydroxychalcones bearing methoxy substituents were synthesized, among which five are new. The NMR data for all synthesized chalcones are described for the first time. The complete assignments of the 1H and 13C NMR data can be used for the identification of newly discovered and widely isolated, synthesized chalcones. Copyright

Synthesis and crystal structure of chalcones as well as on cytotoxicity and antibacterial properties

A series of chalcones derivatives were synthesized and evaluated for cytotoxic and antibacterial activities in vitro. These modifications changed their bioactivity profile and indicated a combination of SAR analysis toward the substituents in rings A and