367518-86-3

Basic information

• Product Name: 6-[2’-deoxy-3’-O-dimethoxytrityl-5’-O-tert-butyl(dimethyl)silyl-α,β-D-ribofuranose-1’-yl]amino-5-nitro-2-(phenoxylacetyl)amino-3H-pyrimidine-4-one
• Synonyms: 6-[2’-deoxy-3’-O-dimethoxytrityl-5’-O-tert-butyl(dimethyl)silyl-α,β-D-ribofuranose-1’-yl]amino-5-nitro-2-(phenoxylacetyl)amino-3H-pyrimidine-4-one
• CAS NO: 367518-86-3
• Molecular Weight: 838.002
• Mol File: 367518-86-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-[2’-deoxy-3’-O-dimethoxytrityl-5’-O-tert-butyl(dimethyl)silyl-α,β-D-ribofuranose-1’-yl]amino-5-nitro-2-(phenoxylacetyl)amino-3H-pyrimidine-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[2’-deoxy-3’-O-dimethoxytrityl-5’-O-tert-butyl(dimethyl)silyl-α,β-D-ribofuranose-1’-yl]amino-5-nitro-2-(phenoxylacetyl)amino-3H-pyrimidine-4-one(367518-86-3)
• EPA Substance Registry System: 6-[2’-deoxy-3’-O-dimethoxytrityl-5’-O-tert-butyl(dimethyl)silyl-α,β-D-ribofuranose-1’-yl]amino-5-nitro-2-(phenoxylacetyl)amino-3H-pyrimidine-4-one(367518-86-3)

Safety Data

• Hazardous Substances Data: 367518-86-3(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 367518-76-1 2-deoxy-3-O-dimethoxytrityl-5-O-tert-butyl(dimethyl)silyl-α,β-D-erythropentofuranosyl azide 
• 367518-85-2 (2R,3S)-5-Azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-ol 
• 367518-84-1 3,5-di-O-acetyl-2-deoxy-D-ribofuranosyl azide 
• 418760-15-3 2-deoxy-α,β-D-erythropentofuranosyl azide 
• 4594-52-9 1,3,5-tri-O-acetyl-2-deoxyribose 
• 367518-77-2 6-[2’-deoxy-3’-O-dimethoxytrityl-5’-O-tert-butyl(dimethyl)silyl-α,β-D-ribofuranose-1’-yl]amino-2-amino-5-nitropyrimidine-3H-4-one 
• 122-59-8 2-phenoxyacetic acid 

Downstream Products

• 367518-79-4 C₅₅H₆₆N₇O₁₇PSi 
• 367518-78-3 6-[2’-deoxy-3’-O-dimethoxytrityl-β-D-ribofuranose-1’-yl]amino-5-nitro-2-(phenoxylacetyl)amino-3H-pyrimidine-4-one 
• 367518-81-8 6-[2’-deoxy-3’-O-dimethoxytrityl-α-D-ribofuranose-1’-yl]amino-5-nitro-2-(phenoxylacetyl)amino-3H-pyrimidine-4-one 

Relevant articles and documents

SOLID-PHASE SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING N6-(2-DEOXY-ALPHA,BETA-DERYTHROPENTOFURANOSYL)-2,6-DIAMINO-4-HYDROXY-5-FORMAMIDOPYRIMIDINE (Fapy.dG)

A strategy using reverse phosphoramidites for synthesizing oligonucleotides containing Fapy.dG is disclosed.

Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues

Oligodeoxynucleotides containing formamidopyrimidine lesions and C-nucleoside analogues at defined sites were prepared by solid-phase synthesis and in some cases enzymatic ligation. Formamidopyrimidine lesions were introduced as dinucleotides to prevent r