368-91-2

Basic information

• Product Name: Benzenesulfonyl fluoride, 4-methoxy-
• CAS NO: 368-91-2
• Molecular Formula: C7H7FO3S
• Molecular Weight: 190.195
• Mol File: 368-91-2.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: Benzenesulfonyl fluoride, 4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonyl fluoride, 4-methoxy-(368-91-2)
• EPA Substance Registry System: Benzenesulfonyl fluoride, 4-methoxy-(368-91-2)

Safety Data

• Hazardous Substances Data: 368-91-2(Hazardous Substances Data)

Upstream product

• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 
• 2564-83-2 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 104-94-9 4-methoxy-aniline 
• 1129-26-6 4-methoxybenzene sulfonamide 
• 696-63-9 4-Methoxybenzenethiol 
• 119752-83-9 1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 1153-43-1 4,4'-dimethoxyphenyl thiosulfonate 
• 5335-87-5 4,4'-dimethoxyphenyl disulfide 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 7789-21-1 fluorosulphonic acid 

Downstream Products

• 1129-26-6 4-methoxybenzene sulfonamide 
• 321-10-8 4-methoxy-3-nitro-benzenesulfonyl fluoride 
• 447459-97-4 2,2,2-trifluoro-N-{1-[4-(4-methoxy-benzenesulfonyl)-phenyl]-ethyl}-acetamide 
• 725208-56-0 C₂₂H₃₀N₂O₅S₂ 
• 123412-33-9 1-<<(4-methoxyphenyl)sulfonyl>oxy>naphthalene 
• 560097-81-6 1-((4-methoxyphenyl)sulfonyl)-1H-pyrazole 
• 13046-67-8 Dimethyloxosulfonium-<4-methoxy-phenyl>-sulfonyl-methylid 
• 68162-87-8 4-methoxy-N-(1-phenylethyl)benzenesulfonamide 
• 106555-68-4 N-(4-methoxyphenylsulfonyl)-N-(tert-butyl)amine 

Relevant articles and documents

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Copper-catalyzed three-component reaction of arylhydrazine hydrochloride, DABSO, and NFSI for the synthesis of arenesulfonyl fluorides

This paper reports a convenient copper-catalyzed three-component conversion of arylhydrazine hydrochlorides to arenesulfonyl fluorides in good yields under mild conditions, using 1,4-diazabicyclo [2.2.2]octane bis(sulfur dioxide) (DABSO) as a sulfonyl source andN-fluorobenzenesulfonimide (NFSI) as a fluorine source based on a radical sulfur dioxide insertion and fluorination strategy. Notably, arylhydrazine hydrochloride is used as a safe precursor of aryl radicals.

Metal-Free Visible-Light Synthesis of Arylsulfonyl Fluorides: Scope and Mechanism

The first metal-free procedure for the synthesis of arylsulfonyl fluorides is reported. Under organo-photoredox conditions, aryl diazonium salts react with a readily available SO2 source (DABSO) to afford the desired product through simple nucleophilic fluorination. The reaction tolerates the presence of both electron-rich and -poor aryls and demonstrated a broad functional group tolerance. To shed the light on the reaction mechanism, several experimental techniques were combined, including fluorescence, NMR, and EPR spectroscopy as well as DFT calculations.