368450-56-0Relevant articles and documents
Synthesis and anticancer activity of novel chiral D-glucose derived bis-imidazoles and their analogs
Zhou, Chenghe,Hassner, Alfred
, p. 313 - 326 (2007/10/03)
A series of novel D-glucose derived bis-imidazoles and their analogs, which possess potential in bioorganic and supramolecular chemistry, were designed and synthesized from methyl α-D-glucoside through protection, bis-bromination, N-alkylation and deprotection. All new compounds were characterized by HRMS, 1H, 13C and DEPT NMR spectroscopy as well as elemental analysis. The 1H-1H and 1H-13C 2D NMR spectra for some compounds were also recorded. Some regular features of 13C and 1H NMR spectra were summarized. The anticancer activity of some compounds was evaluated.