36934-45-9 Usage
Description
1-4'-acetyl-[1,1'-biphenyl]-4-yl-2-bromoethan-1-one is an organic compound that serves as an intermediate or impurity in the synthesis of Daclatasvir (D101500), a potent inhibitor of the Hepatitis C Virus (HCV) protein NS5A. 1-4'-acetyl-[1,1'-biphenyl]-4-yl-2-bromoethan-1-one plays a crucial role in the development of pharmaceuticals targeting HCV, contributing to the treatment of hepatitis C.
Uses
Used in Pharmaceutical Industry:
1-4'-acetyl-[1,1'-biphenyl]-4-yl-2-bromoethan-1-one is used as an intermediate/impurity for the synthesis of Daclatasvir (D101500), a drug candidate for the treatment of hepatitis C (HCV). Its role in the development of this antiviral medication is significant, as it helps in the inhibition of the HCV protein NS5A, which is essential for the virus's replication and assembly. By targeting this protein, Daclatasvir can effectively combat the hepatitis C virus and contribute to the treatment of the disease.
Check Digit Verification of cas no
The CAS Registry Mumber 36934-45-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,9,3 and 4 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 36934-45:
(7*3)+(6*6)+(5*9)+(4*3)+(3*4)+(2*4)+(1*5)=139
139 % 10 = 9
So 36934-45-9 is a valid CAS Registry Number.
36934-45-9Relevant articles and documents
PROCESS FOR THE PREPARATION OF DACLATASVIR
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, (2016/11/21)
The present disclosure provides a novel process for the preparation of daclatasvir or pharmaceutically acceptable salts thereof using novel intermediates. Formula (I)
