3695-80-5 Usage
General Description
H-ALA-D-ALA-OH is a dipeptide composed of two alanine amino acids linked together by a peptide bond. The molecule is commonly used in the synthesis of antibiotics, particularly in the formation of peptidoglycan, a component of bacterial cell walls. The presence of H-ALA-D-ALA-OH inhibits the action of the enzyme transpeptidase, which is crucial for the cross-linking of peptidoglycan strands. This disruption of cell wall formation ultimately leads to bacterial cell lysis and death. H-ALA-D-ALA-OH is therefore an important chemical in the development of antibiotic drugs targeting bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 3695-80-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,9 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3695-80:
(6*3)+(5*6)+(4*9)+(3*5)+(2*8)+(1*0)=115
115 % 10 = 5
So 3695-80-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H12N2O3/c1-3(7)5(9)8-4(2)6(10)11/h3-4H,7H2,1-2H3,(H,8,9)(H,10,11)/t3?,4-/m1/s1
3695-80-5Relevant articles and documents
The peptide formation mediated by cyanate revisited. N-carboxyanhydrides as accessible intermediates in the decomposition of N-carbamoylamino acids
Danger, Gregoire,Boiteau, Laurent,Cottet, Herve,Pascal, Robert
, p. 7412 - 7413 (2007/10/05)
Similar to many ureas, N-carbamoylamino acids were shown to be hydrolyzed in aqueous solution through elimination mechanisms at close to neutral pH, the nucleophilic attack of water being a minor process. Two competing elimination mechanisms can take place involving either cyanate or isocyanate transient intermediates. Peptide formation was observed and attributed to the latter pathway through the intermediacy of amino acid N-carboxyanhydride (NCA). Eventually, cyanate and its precursors (including urea) unexpectedly behave as amino acid activating agents because of their ability in amino acid carbamoylation. Owing to its ability to generate a background prebiotic production of NCAs on the primitive Earth, this reaction is suggested to have contributed to the origin of life process. Copyright
