370064-63-4Relevant articles and documents
Design and synthesis of MMP inhibitors using N-arylsulfonylaziridine hydroxamic acids as constrained scaffolds
Hanessian, Stephen,Moitessier, Nicolas,Cantin, Louis-David
, p. 6885 - 6900 (2007/10/03)
The synthesis of cis- and trans-aziridine hydroxamic acid derivatives as MMP inhibitors is described using enantio- and diastereoselective methods for the formation of trisubstituted aziridines. Their preliminary inhibitory activity is reported and discus