37059-57-7

Basic information

• Product Name: 2-(ETHYLAMINO)PYRIDINE
• Synonyms: 2-(ETHYLAMINO)PYRIDINE;N-(2-Pyridinyl)ethanamine;N-(2-Pyridyl)ethanamine;N-Ethyl-2-pyridinamine;N-Ethyl-N-(2-pyridinyl)amine
• CAS NO: 37059-57-7
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.17
• Mol File: 37059-57-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 82 °C / 3.8mmHg
• Flash Point: 85.978 °C
• Appearance: /
• Density: 1.03 g/cm³
• Refractive Index: 1.5600 to 1.5640
• PKA: 6.71±0.10(Predicted)
• CAS DataBase Reference: 2-(ETHYLAMINO)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(ETHYLAMINO)PYRIDINE(37059-57-7)
• EPA Substance Registry System: 2-(ETHYLAMINO)PYRIDINE(37059-57-7)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36
• Hazardous Substances Data: 37059-57-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 67, p. 4965, 2002 DOI: 10.1021/jo020057z

Upstream product

• 67-56-1 methanol 
• 139230-78-7 2-(N-ethyl-2-pyridylamino)-5,5-dimethyl-1,3,2-dioxaphosphorinane 

Downstream Products

• 70720-85-3 N-benzyl-N-ethylpyridin-2-amine 

Relevant articles and documents

SYNTHESIS AND FEATURES OF CHEMICAL BEHAVIOR OF P(III)-PHOSPHORYLATED 2-AMINOPYRIDINES AND THEIR DERIVATIVES

A series of derivatives of 2-aminopyridine, 2-(ethylamino)pyridine, and 1-ethyl-2-imino-1,2-dihydropyridine formed with diisopropylphosphinous esters were obtained.The structure of the compounds was studied. (2-Pyridylamino)diisopropylphosphine was alkylated with triethyloxonium tetrafluoroborate to a quasiphosphonium salt and was protonated with hydrogen chloride at the endocyclic nitrogen atom to give a pyridinium salt.Protonation with fluoroboric acid results in a complex mixture of three products.The methanolysis of P(III)-phosphorylated 2-aminopyridines and their derivatives was studied.These investigations demonstrated that amides capable of prototropic transformations exhibit markedly enhanced phosphorylating activity.