3706-26-1 Usage
Description
4-Methoxyamphetamine hydrochloride, also known as 4-MA, is a serotonergic drug belonging to the amphetamine class. It shares structural and pharmacological similarities with 3,4-methylenedioxymethamphetamine and is considered a potent hallucinogen. Its primary mode of action is through its effects on serotonergic transmission and by reversibly inhibiting the enzyme monoamine oxidase-A (MAO-A). 4-methoxyamphetamine hydrochloride is primarily intended for research and forensic applications.
Uses
Used in Pharmaceutical Research:
4-Methoxyamphetamine hydrochloride is used as a research compound for studying its effects on serotonergic transmission and its potential as a hallucinogen. It aids in understanding the mechanisms of action and the development of new therapeutic agents for various conditions.
Used in Forensic Applications:
In forensic science, 4-Methoxyamphetamine hydrochloride is utilized for the identification and analysis of this substance in biological samples, such as blood or urine. This helps in cases involving drug abuse or intoxication, as well as in the investigation of criminal activities related to the use, distribution, or manufacturing of controlled substances.
Used in Drug Development:
4-Methoxyamphetamine hydrochloride serves as a starting point for the development of new drugs with potential applications in treating various psychiatric and neurological disorders. Its serotonergic activity and reversible MAO-A inhibition make it a valuable compound for exploring novel therapeutic approaches.
Used in Neuropharmacological Studies:
4-Methoxyamphetamine hydrochloride is employed as a research tool in neuropharmacology to investigate the role of serotonin in the central nervous system. This helps researchers understand the underlying mechanisms of various psychiatric conditions and develop targeted treatments.
Used in Toxicological Research:
4-methoxyamphetamine hydrochloride is used in toxicological research to study the potential adverse effects of 4-Methoxyamphetamine hydrochloride on human health. This information is crucial for establishing safety profiles and setting guidelines for its use in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3706-26-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,0 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3706-26:
(6*3)+(5*7)+(4*0)+(3*6)+(2*2)+(1*6)=81
81 % 10 = 1
So 3706-26-1 is a valid CAS Registry Number.
3706-26-1Relevant articles and documents
Synthesis of primary sec-alkylamines via nucleophilic ring-opening of N-phosphorylated aziridines
Gajda, Tadeusz,Napieraj, Anna,Osowska-Pacewicka, Krystyna,Zawadzki, Stefan,Zwierzak, Andrzej
, p. 4935 - 4946 (2007/10/03)
The novel ring-opening reaction of various 2-alkyl- and 2,2-dimethyl-N-(diethoxyphosphoryl)aziridines (1) and (10) with copper-modified Grignard reagents proceeds regiospecifically at the less hindered carbon. The diethyl N-sec-alkylphosphoramidates (2) thus obtained may efficiently be converted to primary sec-alkylamine hydrochlorides (3) by refluxing with 20% hydrochloric acid. 2,3-Disubstituted N-phosphorylated aziridines except N-phosphorylated cyclohexenimine (4) do not react under the described conditions. Copper-mediated reaction of 2-phenyl-N-(diethoxyphosphoryl)aziridine (7) with Grignard reagents affords a mixture of regioisomers (8) and (9) but still with the preference of ring-opening at the carbon of lesser substitution.
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.