37061-97-5Relevant articles and documents
Photoassisted diversity-oriented synthesis: Intramolecular cycloadditions of photogenerated azaxylylenes with oxazole pendants, and subsequent postphotochemical multicomponent modifications
Kumar, N. N. Bhuvan,Kutateladze, Andrei G.
supporting information, p. 460 - 463 (2016/02/18)
Photogenerated aza-o-xylylenes undergo intramolecular cycloaddition reactions to tethered oxazoles, with primary photoproducts featuring a reactive cyclic imine moiety suitable for multicomponent postphotochemical transformations. For example, the reactio
Chain extension of amino acid skeletons: Preparation of ketomethylene isosteres
Theberge, Cory R.,Zercher, Charles K.
, p. 1521 - 1527 (2007/10/03)
Ketomethylene isosteric replacements for peptide bonds were generated through a zinc carbenoid-mediated chain extension reaction in which a variety of amino acid-derived β-keto esters are converted to γ-keto esters in a single step. The reaction tolerates a variety of protecting groups and amino acid side chains with no epimerization of the amino acid stereocenter.