37118-72-2

Basic information

• Product Name: 4-(p-methoxyphenyl)-2-(1H)-quinolinone
• Synonyms: 4-(p-methoxyphenyl)-2-(1H)-quinolinone
• CAS NO: 37118-72-2
• Molecular Weight: 251.285
• Mol File: 37118-72-2.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 4-(p-methoxyphenyl)-2-(1H)-quinolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(p-methoxyphenyl)-2-(1H)-quinolinone(37118-72-2)
• EPA Substance Registry System: 4-(p-methoxyphenyl)-2-(1H)-quinolinone(37118-72-2)

Safety Data

• Hazardous Substances Data: 37118-72-2(Hazardous Substances Data)

Upstream product

• 127-19-5 N,N-dimethyl acetamide 
• 36192-61-7 2-amino-4'-methoxybenzophenone 
• 610-14-0 2-nitrobenzyl chloride 
• 62-53-3 aniline 
• 768-60-5 4-methoxyphenylacetylen 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 495-18-1 Benzohydroxamic acid 
• 965-01-5 3-(4-methoxyphenyl)-3-oxo-N-phenylpropanamide 
• 1373758-54-3 3-(4-methylphenyl)-5H-1,4,2-dioxazol-5-one 
• 101089-43-4 1-amino-2-[1-(4-methoxyphenyl)ethenyl]benzene 
• 141339-54-0 bis(4-anisyl)iodonium triflate 
• 124-38-9 carbon dioxide 
• 615-43-0 2-iodophenylamine 
• 32117-52-5 1-(1-(4-methoxyphenyl)ethylidene)-2-tosylhydrazine 

Downstream Products

• 37118-73-3 2-chloro-4-(4-methoxyphenyl)quinoline 
• 106015-78-5 2-{4-[4-(4-Methoxy-phenyl)-quinolin-2-yl]-piperazin-1-yl}-ethanol 
• 106015-61-6 2-(4-Ethyl-piperazin-1-yl)-4-(4-methoxy-phenyl)-quinoline 
• 120301-15-7 4-(4-Methoxy-phenyl)-2-piperazin-1-yl-quinoline 

Relevant articles and documents

1,4,2-Dioxazol-5-ones as Isocyanate Equivalents: An Efficient Synthesis of 2-Quinolinones via β-Keto Amides

Under thermal conditions, 1,4,2-dioxazol-5-ones are known to undergo decarboxylation followed by Lossen's rearrangement to yield isocyanates. Described herein is the in situ trapping of the resulting isocyanates with carbon nucleophiles to synthesize β-keto amides. Furthermore, a general and mild method for the conversion of the resulting β-keto amides into quinolin-2-ones is reported.

Synthesis of 2-Quinolinones via a Hypervalent Iodine(III)-Mediated Intramolecular Decarboxylative Heck-Type Reaction at Room Temperature

A hypervalent iodine(III)-mediated intramolecular decarboxylative Heck-type reaction of 2-vinyl-phenyl oxamic acids has been developed. The unique ring-strain-enabled radical decarboxylation mechanism is preliminarily revealed. This protocol features metal-free reaction conditions and operational simplicity, allowing the lactamization of 2-vinylanilines using a readily accessible carbonyl source and the synthesis of various 2-quinolinones with excellent chemoselectivity at room temperature.

Method for preparing 4-aryl-2-quinolinone through carbon dioxide

The invention discloses a method for preparing 4-aryl-2-quinolinone through carbon dioxide, and belongs to the technical field of carbon dioxide comprehensive utilization. The method comprises the following concrete process steps: in a dehydrated and deox