371245-35-1

Basic information

• Product Name: 7-[2,2-bis-(2-hydroxy-4,4-dimethyl-6-oxo-cyclohex-1-enyl)-ethyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
• CAS NO: 371245-35-1
• Molecular Weight: 484.552
• Mol File: 371245-35-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-[2,2-bis-(2-hydroxy-4,4-dimethyl-6-oxo-cyclohex-1-enyl)-ethyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[2,2-bis-(2-hydroxy-4,4-dimethyl-6-oxo-cyclohex-1-enyl)-ethyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione(371245-35-1)
• EPA Substance Registry System: 7-[2,2-bis-(2-hydroxy-4,4-dimethyl-6-oxo-cyclohex-1-enyl)-ethyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione(371245-35-1)

Safety Data

• Hazardous Substances Data: 371245-35-1(Hazardous Substances Data)

Upstream product

• 5614-53-9 1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-yl-acetaldehyd 
• 126-81-8 dimedone 
• 479-18-5 diprophylline 

Relevant articles and documents

Synthesis of new 7-alkylated theophyllines by chemical modification of dyphylline

Acetylation of 7-(2,3-dihydroxyprop-1-yl)theophylline (1) afforded the di-O-acetyl derivative 2. Reaction of 1 with acetone and benzaldehyde gave the 1,3-dioxolane derivatives 4 and 5, respectively. Periodate oxidation of 1 gave theophylline-7-acetaldehyde (6). Treatment of 6 with hydroxylamine hydrochloride, thiosemicarbazide and benzoylhydrazine afforded the corresponding oxime 9, thiosemicarbazone 10 and benzoylhydrazone 11. Treatment of 10 and 11 with boiling acetic anhydride afforded the respective 1,3,4-thiadiazoline 12 and oxadiazoline 13. Condensation of 6 with dimedone followed by boiling with dilute hydrochloric acid afforded the xanthene derivative 15.