37150-63-3

Basic information

• Product Name: 1-(acetamidomethyl)cyclohexanol
• Synonyms: 1-(acetamidomethyl)cyclohexanol
• CAS NO: 37150-63-3
• Molecular Weight: 171.239
• Mol File: 37150-63-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(acetamidomethyl)cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(acetamidomethyl)cyclohexanol(37150-63-3)
• EPA Substance Registry System: 1-(acetamidomethyl)cyclohexanol(37150-63-3)

Safety Data

• Hazardous Substances Data: 37150-63-3(Hazardous Substances Data)

Upstream product

• 4000-72-0 1-aminomethylcyclohexanol 
• 108-24-7 acetic anhydride 
• 24247-68-5 5,5-Pentamethylenoxazolidin-2-on 

Downstream Products

• 1223105-66-5 1-O-acetyl-1-[(mesylamido)methyl]cyclohexanol 
• 1223105-65-4 1-O-acetyl-1-[(tosylamido)methyl]cyclohexanol 
• 4000-72-0 1-aminomethylcyclohexanol 

Relevant articles and documents

Sulfonylation-induced N-to O -Acetyl migration in 2-acetamidoethanol derivatives

The first example of sulfonylation-induced N- to O-acetyl migration of 2-acetamidoethanol derivatives is described. This type of reaction could happen with any 2-acetamidoethanol derivatives under typical sulfonylation conditions (TsCl or MsCl, pyridine) and might be a common side reaction of significance. Furthermore, the results reveal that 2-acetamidoethanol derivatives with a sterically encumbered hydroxyl group result in the migration products in high yields. The mechanism of the migration reaction is discussed.