3717-40-6

Basic information

• Product Name: N,N-Dimethyl-1-adamantylamine
• Synonyms: Mrz-2/187;N,N-Dimethyl-1-adamantanamine;N,N-Dimethyl-1-adamantylamine;N,N-Dimethyladamantane-1-amine;N,N-dimethyladamantan-1-amine;N,N-DiMethyl AdaMantylaMine
• CAS NO: 3717-40-6
• Molecular Formula: C₁₂H₂₁N
• Molecular Weight: 179.3018
• Mol File: 3717-40-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 236.3°Cat760mmHg
• Flash Point: 88.2°C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 0.0478mmHg at 25°C
• Refractive Index: 1.528
• CAS DataBase Reference: N,N-Dimethyl-1-adamantylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Dimethyl-1-adamantylamine(3717-40-6)
• EPA Substance Registry System: N,N-Dimethyl-1-adamantylamine(3717-40-6)

Safety Data

• Hazardous Substances Data: 3717-40-6(Hazardous Substances Data)

Usage

General Description

N,N-Dimethyl-1-adamantylamine is a chemical compound that belongs to the family of amines. It is formally derived from adamantane and contains two methyl groups and one amino group attached to the carbon atom. N,N-Dimethyl-1-adamantylamine is commonly used as a reagent in organic synthesis and as a building block for pharmaceuticals and other specialty chemicals. It is also known for its unique molecular structure which makes it highly stable and resistant to degradation. Additionally, N,N-Dimethyl-1-adamantylamine has been studied for its potential applications in various fields including drug delivery, corrosion inhibition, and catalysis. Overall, this compound has versatile properties and potential uses in different industries.

InChI:InChI=1/C12H21N/c1-13(2)12-6-9-3-10(7-12)5-11(4-9)8-12/h9-11H,3-8H2,1-2H3

Upstream product

• 3717-41-7 1-(Dimethylamino)adamantane N-oxide 
• 67-56-1 methanol 
• 24886-73-5 1-Azidoadamantane 

Downstream Products

• 22892-02-0 C₃₄H₆₂N₂⁽²⁺⁾*2I^(1-) 
• 3717-41-7 1-(Dimethylamino)adamantane N-oxide 
• 17933-29-8 7-methylenebicyclo[3.3.1]nonan-3-one 
• 53488-28-1 dinitrate of 1,3-adamantanediol 
• 53075-09-5 N,N,N-trimethyl-1-adamantane ammonium hydroxide 

Relevant articles and documents

Selective synthesis of mono- and di-methylated amines using methanol and sodium azide as C1 and N1 sources

A Ru(ii) complex mediated synthesis of various N,N-dimethyl and N-monomethyl amines from organic azides using methanol as a methylating agent is reported. This methodology was successfully applied for a one-pot reaction of bromide derivatives and sodium azide in methanol. Notably, by controlling the reaction time several N-monomethylated and N,N-dimethylated amines were synthesized selectively. The practical applicability of this tandem process was revealed by preparative scale reactions with different organic azides and synthesis of an anti-vertigo drug betahistine. Several kinetic experiments and DFT studies were carried out to understand the mechanism of this transformation.