37172-84-2

Basic information

• Product Name: Cyclopentaneacetic acid, a-bromo-, methyl ester
• CAS NO: 37172-84-2
• Molecular Formula: C8H13BrO2
• Molecular Weight: 221.094
• Mol File: 37172-84-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclopentaneacetic acid, a-bromo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentaneacetic acid, a-bromo-, methyl ester(37172-84-2)
• EPA Substance Registry System: Cyclopentaneacetic acid, a-bromo-, methyl ester(37172-84-2)

Safety Data

• Hazardous Substances Data: 37172-84-2(Hazardous Substances Data)

Upstream product

• 1122-99-2 2-cyclopentylacetyl chloride 
• 1123-00-8 2-cyclopentylacetic acid 
• 67-56-1 methanol 
• 99644-87-8 2-bromocyclopentylacetylchloride 

Downstream Products

• 86895-83-2 methyl 2-cyclopent-1-enyl-2-phenylthiopropanoate 
• 99683-13-3 methyl 2-cyclopent-1-enyl-3-oxo-3-phenyl-2-phenylthiopropenoate 
• 99683-12-2 methyl 2-cyclopent-1-enyl-3-oxo-2-phenylthiobutanoate 
• 99683-17-7 methyl 3-oxo-2-(2-phenylthiocyclopentylidene)butanoate 
• 86895-71-8 methyl 2-cyclopentyl-2-sulphinylacetate 
• 66716-67-4 methyl cyclopentylidenephenylthioacetate 
• 900535-56-0 3-{1-(4-chloro-benzyl)-2-[4-(1-cyclopentyl-2-diethylamino-ethyl)-piperazin-1-yl]-2-oxo-ethylcarbamoyl}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 86895-66-1 methyl 2-cyclopentyl-2-phenylthioacetate 

Relevant articles and documents

ACYLATION OF EXTENDED ENOLATE IONS FROM α-PHENYLTHIO(PhS-)CROTONATE ESTERS

C-Acylation, like alkylation, occurs at the α-position of title compounds to give unsaturated keto-esters from which the PhS group may be removed.

Privileged structure based ligands for melanocortin-4 receptors-Aliphatic piperazine derivatives

Aliphatic carbocyclic replacement of the benzyl group of compound 1 yielded compounds with high affinity for the melanocortin-4 receptor (MC4R). Compounds with a cyclohexyl group showed a consistent high affinity, while different polar groups with less basicity were good replacements for the original diethyl amines. Substitution of the polar group found in these privileged structures with an aliphatic moiety produced compounds with high affinity for MC4R.

ALKYLATION OF EXTENDED ENOLATES FROM α-PHENYLTHIO CROTONATE ESTERS

Conditions are described for the formation of enolate anions from substituted α-phenylthio-crotonate esters and their alkylation at the α-carbon atom.