3721-35-5

Basic information

• Product Name: 2-Propenoyl chloride, 3-chloro-, (Z)-
• Synonyms: 2-Propenoyl chloride,3-chloro-,(Z);cis-3-chloroacryloyl chloride;2-Propenoyl chloride,3-chloro;Z-3-chloroacryloyl chloride;3-chloroacrylic acid chloride;(Z)-2-chlorovinylcarbonyl chloride;3-cis-chloroacryloyl chloride
• CAS NO: 3721-35-5
• Molecular Formula: C3H2Cl2O
• Molecular Weight: 124.954
• Mol File: 3721-35-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 63-64 °C(Press: 51-53 Torr)
• Density: 1.364±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Propenoyl chloride, 3-chloro-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoyl chloride, 3-chloro-, (Z)-(3721-35-5)
• EPA Substance Registry System: 2-Propenoyl chloride, 3-chloro-, (Z)-(3721-35-5)

Safety Data

• Hazardous Substances Data: 3721-35-5(Hazardous Substances Data)

Upstream product

• 1609-93-4 3-chloroacrylic acid 
• 2345-61-1 (E)-3-chloroacrylic acid 
• 471-25-0 Propiolic acid 

Downstream Products

• 220699-88-7 N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-3(E)-chloro-2-propenamide 
• 92180-14-8 (+)-8-phenylmenthyl (Z)-3-chloroacrylate 

Relevant articles and documents

FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to a class of fused pyrimidine compounds of Formula I, their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to a process of preparation of these fused pyrimidine compounds, and to pharmaceutical compositions containing them.

MIXED COMPOSITIONS FOR CONTROLLING PARASITIC INSECTS

The present invention relates to a mixture composition for controlling ectoparasites of mammals and birds, comprising as active ingredients a compound of formula (I) or a salt thereof and one or more compounds selected from the group consisting of pyrethroid insecticides. The composition according to the present invention has high control effect against resistant ectoparasites, can quickly act, and is safe. wherein R1 represents optionally substituted alkyl; optionally substituted alkenyl; optionally substituted alkynyl; OR5 wherein R5 represents optionally substituted alkyl, optionally substituted alkenyl, or optionally substituted alkynyl; or SR5 wherein R5 is as defined above, R2 represents optionally substituted alkyl, any one of R3 and R4 represents hydrogen and the other represents fluorine, chlorine, bromine, or CF3, and X represents fluorine or chlorine.

Stereoselectivity and Generality of the Palladium-Catalysed Cyclopropanation of α,β-Unsaturated Carboxylic Acids Derivatized with Oppolzer's Sultam

A series of α,β-unsaturated carboxylic acids derivatized with camphorsultam 1 a s a chiral auxiliary has been stereoselectively cyclopropanated. the selectivity of the reaction produces cyclopropanated products with the 1R,2R absolute configuration as indicated by the optical rotations as well as by an X-ray structure determineation.The temperature dependence of the reaction was studied with three substrates. the highest stereoselectivity was obtained at temperatures above 25 deg C.Branching at the α- or β-carbons disfavours complete conversion, and electron-withdrawing substituents at these positions seem to prevent the reaction.The auxiliary was removed by using titanium(IV) isopropoxide in benzyl alcohol followed by alkaline hydrolysis of the intermediate ester. the potent 5-HT1A receptor agonist (1R,2S)-2-(2-hydroxyphenyl)-N,N-dipropylcyclopropylamine 13 was synthesized by this method