372522-94-6Relevant articles and documents
Statistical molecular design, parallel synthesis, and biological evaluation of a library of thrombin inhibitors
Linusson,Gottfries,Olsson,?rnskov,Folestad,Nordén,Wold
, p. 3424 - 3439 (2007/10/03)
A library of thrombin inhibitors has been designed using statistical molecular design. An aromatic scaffold was used, with three varied positions corresponding to three pockets at the active site of thrombin (the S-, P-, and D-pockets). The selection was
