37394-53-9Relevant articles and documents
Azole derivatives as histamine H3 receptor antagonists, Part 2: C-C and C-S coupled heterocycles
Walter,Isensee,Kottke,Ligneau,Camelin,Schwartz,Stark
scheme or table, p. 5883 - 5886 (2010/11/18)
With a small series of compounds we demonstrated the variability in the core region of the human histamine H3 receptor (hH3R) antagonist structural blueprint by introducing polar azole groups (oxazole, oxadiazole, thiazole and triazole). Additional variations achieved by coupling different residues to the heterocyclic core structure led to further optimisation of in vitro receptor binding of the novel azole derivatives.
Synthesis of a novel pyrrole oxazole analogue of the insecticide pirate
Loughlin, Wendy A.,Murphy, Michelle E.,Elson, Kathryn E.,Henderson, Luke C.
, p. 227 - 232 (2007/10/03)
The pyrrole oxazole 4 is a novel analogue of the broad-spectrum insecticide and miticide pirate 2. The expedient synthesis of pyrrole oxazole 4 in six steps from pyrrole is reported using a synthetic route that could have potential for the solution-phase