374-99-2 Usage
Description
2,2,3,3,4,4,4-HEPTAFLUOROBUTYLAMINE is a clear colorless liquid that serves as a crucial intermediate in the pharmaceutical industry. Its unique chemical properties make it a valuable component in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
2,2,3,3,4,4,4-HEPTAFLUOROBUTYLAMINE is used as a pharmaceutical intermediate for the synthesis of various drugs. Its chemical properties allow it to be a key component in the development of new medications, contributing to the advancement of pharmaceutical research and drug discovery.
As a pharmaceutical intermediate, 2,2,3,3,4,4,4-HEPTAFLUOROBUTYLAMINE plays a significant role in the following applications:
1. Drug Synthesis: It is used in the synthesis of various pharmaceutical compounds, providing a foundation for the development of new drugs with potential therapeutic benefits.
2. Research and Development: Its unique chemical properties make it an essential tool in the research and development of novel pharmaceuticals, enabling scientists to explore new avenues in drug discovery and design.
3. Drug Delivery Systems: 2,2,3,3,4,4,4-HEPTAFLUOROBUTYLAMINE may also be utilized in the development of innovative drug delivery systems, enhancing the bioavailability and efficacy of medications.
Check Digit Verification of cas no
The CAS Registry Mumber 374-99-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,7 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 374-99:
(5*3)+(4*7)+(3*4)+(2*9)+(1*9)=82
82 % 10 = 2
So 374-99-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H4F7N/c5-2(6,1-12)3(7,8)4(9,10)11/h1,12H2/p+1
374-99-2Relevant articles and documents
Biomimetic reductive amination under the continuous-flow reaction conditions
Soloshonok, Vadim A.,Catt, Hector T.,Ono, Taizo
body text, p. 261 - 265 (2010/04/05)
This study present a full account of continuous-flow reaction conditions for biomimetic reductive amination of fluorinated carbonyl compounds to corresponding amines and amino acids of biomedical importance. We demonstrate that simple silica-adsorbed DBU can be used as efficient catalysts for on-column 1,3-proton shift reaction, a key transformation in the biomimetic reductive amination process. This new on-column process features operationally convenient conditions, higher chemical yields, enantioselectivity and purity of the corresponding products as compared with traditional in-flask reactions. Moreover the removal of base-catalyst, the most delicate problem of the in-flask reactions, is not an issue in the on-column process, as the silica-adsorbed DBU or polymer-bound guanidine remains on the column and can be reused. This feature renders the overall process substantially more economical and synthetically efficient, in particular, for large-scale synthesis of the corresponding fluorinated amines and amino acids target.