374073-86-6Relevant articles and documents
Secondary Phosphine Oxide Preligands for Palladium-Catalyzed C–H (Hetero)Arylations: Efficient Access to Pybox Ligands
Ghorai, Debasish,Müller, Valentin,Keil, Helena,Stalke, Dietmar,Zanoni, Giuseppe,Tkachenko, Boryslav A.,Schreiner, Peter R.,Ackermann, Lutz
supporting information, p. 3137 - 3141 (2017/09/06)
C–H arylations of oxazolines were accomplished with a well-defined palladium catalyst derived from a secondary bisdiamantyl phosphine oxide. The single-component secondary phosphine oxide (SPO)-palladium complex enabled C–H activations with aryl bromides
1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)
Heerding, Dirk A.,Chan, George,DeWolf Jr., Walter E.,Fosberry, Andrew P.,Janson, Cheryl A.,Jaworski, Deborah D.,McManus, Edward,Miller, William H.,Moore, Terrance D.,Payne, David J.,Qiu, Xiayang,Rittenhouse, Stephen F.,Slater-Radosti, Courtney,Smith, Ward,Takata, Dennis T.,Vaidya, Kalindi S.,Yuan, Catherine C.K.,Huffman, William F.
, p. 2061 - 2065 (2007/10/03)
1,4-Disubstituted imidazole inhibitors of Staphylococcus aureus and Escherichia coli enoyl acyl carrier protein reductase (FabI) have been identified. Crystal structure data shows the inhibitor 1 bound in the enzyme active site of E. coli FabI.
