37428-88-9Relevant articles and documents
Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents
Habib, Monica M. W.,Abdelfattah, Mohamed A. O.,Abadi, Ashraf H.
, p. 868 - 874 (2015/12/24)
Eighteen new 5-benzylidene-3-(4-arylpiperazin-1-ylmethyl)-2-thioxo-imidazolidin-4-ones were designed as hybrid structures from previously reported anticonvulsant compounds, synthesized and tested for anticonvulsant activity. Initial anticonvulsant screeni
Glycine derivatives of imidazolones as potential ligands of glycine binding site of NMDA receptors. Part 1
Kiec-Kononowicz, Katarzyna,Karolak-Wojciechowska, Janina,Handzlik, Jadwiga
, p. 381 - 388 (2007/10/03)
The series of glycine derivatives of diphenyl or (un)substituted arylidene imidazolones was designed and obtained as potential ligands of the glycine binding site of NMDA receptors. The compounds were evaluated in vitro for their affinity to the glycine b