374600-85-8

Basic information

• Product Name: 1,3-dimethyl-7-(3-phenylpropyl)-3,7-dihydro-1H-purine-2,6-dione
• Synonyms: 1,3-dimethyl-7-(3-phenylpropyl)-3,7-dihydro-1H-purine-2,6-dione
• CAS NO: 374600-85-8
• Molecular Weight: 298.345
• Mol File: 374600-85-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-dimethyl-7-(3-phenylpropyl)-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dimethyl-7-(3-phenylpropyl)-3,7-dihydro-1H-purine-2,6-dione(374600-85-8)
• EPA Substance Registry System: 1,3-dimethyl-7-(3-phenylpropyl)-3,7-dihydro-1H-purine-2,6-dione(374600-85-8)

Safety Data

• Hazardous Substances Data: 374600-85-8(Hazardous Substances Data)

Upstream product

• 68696-86-6 N⁷-tosyltheophylline 
• 122-97-4 3-Phenyl-1-propanol 
• 58-55-9 theophylline 

Relevant articles and documents

N 7-Tosyltheophylline (TsTh): A highly efficient reagent for the one-pot synthesis of n 7-alkyltheophyllines from alcohols

A convenient and highly efficient one-pot N-alkylation of theophylline from alcohols via N 7-tosyltheophylline (TsTh) is described. In this protocol, the treatment of primary and/or secondary alcohols with a mixture of TsTh and 1,8-diazabicyclo[5.4.0]undec-7-ene in refluxing acetonitrile affords the corresponding N 7-alkyltheophylline in good to excellent yields; the reaction was optimized for solvent and base. This methodology is highly efficient for various structurally diverse primary and secondary alcohols. A plausible mechanism for the one-pot N-alkylation of theophylline with alcohols via TsTh has been suggested. Georg Thieme Verlag Stuttgart New York.