374792-67-3

Basic information

• Product Name: cis-(RS)- and trans-(RS)-α-methyl-N-{4-[4-hydroxymethyl-4-(methoxymethyl)piperidin-1-yl]-1-phenylcyclohexyl}-3,5-bis(trifluoromethyl)benzeneacetamide
• Synonyms: cis-(RS)- and trans-(RS)-α-methyl-N-{4-[4-hydroxymethyl-4-(methoxymethyl)piperidin-1-yl]-1-phenylcyclohexyl}-3,5-bis(trifluoromethyl)benzeneacetamide
• CAS NO: 374792-67-3
• Molecular Weight: 600.645
• Mol File: 374792-67-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cis-(RS)- and trans-(RS)-α-methyl-N-{4-[4-hydroxymethyl-4-(methoxymethyl)piperidin-1-yl]-1-phenylcyclohexyl}-3,5-bis(trifluoromethyl)benzeneacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: cis-(RS)- and trans-(RS)-α-methyl-N-{4-[4-hydroxymethyl-4-(methoxymethyl)piperidin-1-yl]-1-phenylcyclohexyl}-3,5-bis(trifluoromethyl)benzeneacetamide(374792-67-3)
• EPA Substance Registry System: cis-(RS)- and trans-(RS)-α-methyl-N-{4-[4-hydroxymethyl-4-(methoxymethyl)piperidin-1-yl]-1-phenylcyclohexyl}-3,5-bis(trifluoromethyl)benzeneacetamide(374792-67-3)

Safety Data

• Hazardous Substances Data: 374792-67-3(Hazardous Substances Data)

Upstream product

• 240401-27-8 2-oxa-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester 
• 374791-10-3 (RS)-α-methyl-N-[4-oxo-1-phenylcyclohexyl]-3,5-bis(trifluoromethyl)benzeneacetamide 

Relevant articles and documents

Cyclohexane derivatives and their use as therapeutic agents

The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R17, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.