374794-94-2 Usage
General Description
1-Oxa-8-azaspiro[4.5]decane, 2,2-dimethyl- is a chemical compound with a spirocyclic structure. It contains a heterocyclic oxygen atom and a nitrogen atom, and has two methyl groups attached to the spiro carbon. 1-Oxa-8-azaspiro[4.5]decane, 2,2-dimethyl- is used in organic synthesis and pharmaceutical research, where its unique structure and functional groups can be leveraged to create new compounds with potentially valuable properties. Its spirocyclic nature also gives it the potential to exhibit interesting biological activities. Additionally, its 2,2-dimethyl substitution pattern may confer unique chemical reactivity and physical properties, making it a valuable building block in the development of new molecules for a variety of applications.
Check Digit Verification of cas no
The CAS Registry Mumber 374794-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,4,7,9 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 374794-94:
(8*3)+(7*7)+(6*4)+(5*7)+(4*9)+(3*4)+(2*9)+(1*4)=202
202 % 10 = 2
So 374794-94-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H19NO/c1-9(2)3-4-10(12-9)5-7-11-8-6-10/h11H,3-8H2,1-2H3
374794-94-2Relevant articles and documents
TETRAHYDROPYRAN COMPOUNDS AS TACHYKININ ANTAGONISTS
-
Page 80-81, (2010/02/08)
The present invention relates to the compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and W are as defined herein, and pharmaceutically acceptable salts thereof; the compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.
4,4-Disubstituted cyclohexylamine NK1 receptor antagonists II
Cooper, Laura C.,Carlson, Emma J.,Castro, Jose L.,Chicchi, Gary G.,Dinnell, Kevin,Di Salvo, Jerry,Elliott, Jason M.,Hollingworth, Gregory J.,Kurtz, Marc M.,Ridgill, Mark P.,Rycroft, Wayne,Tsao, Kwei-Lan,Swain, Christopher J.
, p. 1759 - 1762 (2007/10/03)
A series of novel 4,4-disubstituted cyclohexylamines as NK1 receptor antagonists is described: modifications to the amine moiety retain NK1 receptor binding affinity whilst disrupting IKr affinity.
