375345-67-8Relevant articles and documents
Synthesis of DNA templates containing the fifth base, 2-amino-6-(dimethylamino)purine, for specific transcription involving unnatural base pairs
Hirao, Ichiro,Nojima, Takahiko,Mitsui, Tsuneo,Yokoyama, Shigeyuki
, p. 914 - 915 (2007/10/03)
An unnatural nucleobase, pyridin-2-one (denoted as y), can be specifically incorporated into RNA opposite 2-amino-6-(dimethylamino)purine (denoted as x) in DNA templates by T7 RNA polymerase. For the easy preparation of DNA templates containing x, protect