375345-97-4

Basic information

• Product Name: (R)-N-(2-phenylpropyl)propane-2-sulfonaMide
• Synonyms: (R)-N-(2-phenylpropyl)propane-2-sulfonaMide
• CAS NO: 375345-97-4
• Molecular Formula: C₁₂H₁₉NO₂S
• Molecular Weight: 241.34976
• Mol File: 375345-97-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-N-(2-phenylpropyl)propane-2-sulfonaMide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-(2-phenylpropyl)propane-2-sulfonaMide(375345-97-4)
• EPA Substance Registry System: (R)-N-(2-phenylpropyl)propane-2-sulfonaMide(375345-97-4)

Safety Data

• Hazardous Substances Data: 375345-97-4(Hazardous Substances Data)

Upstream product

• 10147-37-2 Isopropylsulfonyl chloride 
• 582-22-9 (R)-2-phenylpropylamine 
• 685876-10-2 (2R)-2-phenylpropylamine Malate 
• 34298-25-4 (R)-β-methylphenethylamine hydrochloride 
• 1123-85-9 (+)-(R)-2-phenylpropanol 
• 112424-29-0 (R)-2-(2-phenylpropyl)isoindoline-1,3-dione 
• 20780-53-4 (R)-Styrene oxide 
• 1823-91-2 1-phenylethyl cyanide 

Downstream Products

• 375345-98-5 propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide 
• 1449337-13-6 [(2R)-2-(3-nitrophenyl)propyl][(methylethyl)sulfonyl]amine 
• 376594-72-8 R-2-(4-nitrophenyl)-1-(2-propanesulfonamido)-propane 
• 400629-36-9 propane-2-sulfonic acid {2-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenyl]propyl}amide 

Relevant articles and documents

BIVALENT AMPA RECEPTOR POSITIVE ALLOSTERIC MODULATORS

Embodiments of the invention are directed to compounds that are positive allosteric modulators of AMP A receptors.

AMPA RECEPTOR POTENTIATORS

The present invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders.

Combination therapy for treatment of depression

The present invention provides a method for treating depression, comprising administering to a patient an effective amount of a first component which is a suitable antidepressant, in combination with an effective amount of a second component which is a suitable AMPA receptor potentiator.