37535-58-3

Basic information

• Product Name: (R)-N-Boc-(4-Pyridyl)alanine
• Synonyms: RARECHEM BK PT 0243;(R)-2-TERT-BUTOXYCARBONYLAMINO-3-PYRIDIN-4-YL-PROPIONIC ACID;(R)-N-BOC-(4-PYRIDYL)ALANINE;N-ALPHA-T-BUTOXYCARBONYL-3-(4-PYRIDYL)-D-ALANINE;N-ALPHA-T-BOC-BETA-(4-PYRIDYL)-D-ALANINE;N-TERT-BUTOXYCARBONYL-4-PYRIDYL-D-ALANINE;BOC-(R)-2-AMINO-3-(4'-PYRIDYL)PROPANOIC ACID;BOC-BETA-(4-PYRIDYL)-D-ALANINE
• CAS NO: 37535-58-3
• Molecular Formula: C₁₃H₁₈N₂O₄
• Molecular Weight: 266.29
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;Amino Acid Derivatives;a-amino
• Mol File: 37535-58-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 223-229 °C
• Boiling Point: 409.5°C (rough estimate)
• Flash Point: 228.5 °C
• Appearance: White/Powder
• Density: 1.1738 (rough estimate)
• Vapor Pressure: 4.82E-09mmHg at 25°C
• Refractive Index: 1.6450 (estimate)
• Storage Temp.: Store at 0-5°C
• PKA: 3.43±0.10(Predicted)
• Sensitive: Air & Moisture Sensitive
• BRN: 4195478
• CAS DataBase Reference: (R)-N-Boc-(4-Pyridyl)alanine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-Boc-(4-Pyridyl)alanine(37535-58-3)
• EPA Substance Registry System: (R)-N-Boc-(4-Pyridyl)alanine(37535-58-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 37535-58-3(Hazardous Substances Data)

Usage

Chemical Properties

white to off-white powder

InChI:InChI=1/C13H18N2O4/c1-13(2,3)19-12(18)15-10(11(16)17)8-9-4-6-14-7-5-9/h4-7,10H,8H2,1-3H3,(H,15,18)(H,16,17)/p-1/t10-/m1/s1

Upstream product

• 348334-73-6 (R)-2-amino-3-(pyridin-4-yl)-1-propanol 

Downstream Products

• 1021943-61-2 (R)-2-((tert-butoxycarbonyl)amino)-3-(piperidin-4-yl)propanoic acid 
• 1416469-62-9 tert-butyl [(2R)-1-{4-[(4aS,8aR)-4-(3,4-dimethoxyphenyl)-1-oxo-4a,5,6,7,8,8a-hexahydrophthalazin-2(1H)-yl]piperidin-1-yl}-1-oxo-3-(pyridin-4-yl)propan-2-yl]carbamate 
• 1416469-61-8 (4aS,8aR)-2-{1-[(2R)-2-amino-3-(pyridin-4-yl)propanoyl]piperidin-4-yl}-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one 
• 1416468-09-1 4-[5-(cyclopropylmethoxy)-1,3-benzodioxol-4-yl]-N-[(2R)-1-{4-[3-(3,4-dimethoxyphenyl)-5,5-dimethyl-6-oxo-5,6-dihydropyridazin-1(4H)-yl]piperidin-1-yl}-3-(4-fluorophenyl)-1-oxopropan-2-yl]-5H-pyrrolo[3,2-d]pyrimidine-7-carboxamide 
• 277296-73-8 cyclohexanecarboxylic acid{(1R)-2-[4-(2-methoxy-phenyl)-piperidin-1-yl]-1-pyridin-4-ylmethyl-ethyl}-methyl-amide 
• 851685-40-0 (R)-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-2-oxo-1-pyridin-4-ylmethyl-ethyl}-carbamic acid tert-butyl ester 
• 274928-65-3 4-{2-[(R)-1-{[((S)-1-Carbamimidoyl-2-ethoxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-2-(1-carbamimidoyl-piperidin-4-yl)-ethylcarbamoyloxy]-ethyl}-benzoic acid ethyl ester 
• 274928-63-1 N-[(1-carbamimidoyl-2-ethoxy-piperidin-3-ylcarbamoyl)-methyl]-3-(1-carbamimidoyl-piperidin-4-yl)-2-[2-(1H-tetrazol-5-yl)-phenylmethanesulfonylamino]-propionamide 
• 274928-61-9 3-{[(R)-1-{[((S)-1-Carbamimidoyl-2-ethoxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-2-(1-carbamimidoyl-piperidin-4-yl)-ethylsulfamoyl]-methyl}-benzoic acid 

Relevant articles and documents

Fused purine derivatives

A condensed purine derivative represented by Formula (I): wherein X—Y—Z represents R1N—C═O or N═C—W, R2 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted aromatic heterocyclic group, a substituted or unsubstituted alicyclic heterocyclic group or the like, n represents an integer of from 0 to 3, V1 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aromatic heterocyclic group, V2 represents a substituted lower alkyl group or a substituted or unsubstituted aromatic heterocyclic group, and when V1 represents a hydrogen atom, a lower alkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryl group, and for example, X—Y—Z represents R1aN—C═O and R2 represents a substituted lower alkyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted alicyclic heterocyclic group, a halogen atom, a lower alkylthio group, —NR7R8, —CO2H, a lower alkoxycarbonyl group, —COHal, —CONR9R10 or —CHO, V2 may represent a lower alkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryl group; or a pharmacologically acceptable salt thereof.