37539-91-6

Basic information

• Product Name: ethyl 5-chloro-3-phenyl-1,2,4-triazine-6-carboxylate
• Synonyms: 1,2,4-Triazine-6-carboxylic acid, 5-chloro-3-phenyl-, ethyl ester
• CAS NO: 37539-91-6
• Molecular Formula: C₁₂H₁₀ClN₃O₂
• Molecular Weight: 263.6797
• Mol File: 37539-91-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 436.8°C at 760 mmHg
• Flash Point: 218°C
• Density: 1.313g/cm³
• Vapor Pressure: 7.87E-08mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: ethyl 5-chloro-3-phenyl-1,2,4-triazine-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-chloro-3-phenyl-1,2,4-triazine-6-carboxylate(37539-91-6)
• EPA Substance Registry System: ethyl 5-chloro-3-phenyl-1,2,4-triazine-6-carboxylate(37539-91-6)

Safety Data

• Hazardous Substances Data: 37539-91-6(Hazardous Substances Data)

Upstream product

• 36286-76-7 5-oxo-3-phenyl-4,5-dihydro-[1,2,4]triazine-6-carboxylic acid ethyl ester 
• 36286-76-7 ethyl 5-oxo-3-phenyl-4,5-dihydro-1,2,4-triazine-6-carboxylate 
• 1670-14-0 benzamidine monohydrochloride 
• 28819-30-9 benzamidrazone 
• 921620-61-3 5-oxo-3-phenyl-5,6-dihydro-[1,2,4]triazine-6-carboxylic acid ethyl ester 

Downstream Products

• 126542-55-0 5-But-3-ynyloxy-3-phenyl-[1,2,4]triazine-6-carboxylic acid ethyl ester 
• 126542-43-6 3-Phenyl-[1,2,4]triazine-6-carboxylic acid ethyl ester 
• 37539-92-7 ethyl 5-amino-3-phenyl-1,2,4-triazine-6-carboxylate 
• 572920-57-1 5-amino-3-phenyl-1,2,4-triazine-6-carboxamide 

Relevant articles and documents

INHIBITORS OF MITOTIC KINESIN

The present invention relates to compounds useful as inhibitors of KSP and methods for the treatment or prevention of cellular proliferative diseases.

The Chemistry of 1,2,4-Triazines, XIV. - Synthesis and Reactions of 5-Chloro-1,2,4-triazines

5-Chloro-1,2,4-triazines 4 are prepared from 1,2,4-triazin-5(2H)-ones 3 and transfered into 5-amino- (7), 5-cyano (8), and 5-(ω-alkinyloxy)-1,2,4-triazines (9). 7a-d are cyclized to imidazo1,2,4-triazines (10a-d).