37587-81-8

Basic information

• Product Name: propyl dichloroacetate
• Synonyms: propyl dichloroacetate;Dichloroacetic acid propyl ester
• CAS NO: 37587-81-8
• Molecular Formula: C₅H₈Cl₂O₂
• Molecular Weight: 171.02182
• EINECS: 253-555-8
• Mol File: 37587-81-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 173.9°Cat760mmHg
• Flash Point: 64.6°C
• Appearance: /
• Density: 1.241g/cm³
• Vapor Pressure: 1.24mmHg at 25°C
• Refractive Index: 1.444
• CAS DataBase Reference: propyl dichloroacetate(CAS DataBase Reference)
• NIST Chemistry Reference: propyl dichloroacetate(37587-81-8)
• EPA Substance Registry System: propyl dichloroacetate(37587-81-8)

Safety Data

• Hazardous Substances Data: 37587-81-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H8Cl2O2/c1-2-3-9-5(8)4(6)7/h4H,2-3H2,1H3

Upstream product

• 71-23-8 propan-1-ol 
• 302-17-0 chloral hydrate 
• 151-50-8 potassium cyanide 
• 79-43-6 dichloro-acetic acid 
• 75-19-4 cyclopropane 
• 79-36-7 dichloroacethyl chloride 
• 16967-79-6 trichloroethylene epoxide 
• 1768-31-6 pentachloroacetone 
• 100-63-0 phenylhydrazine 
• 146304-82-7 2,2-Dichloro-3-hydroxy-3-thiophen-2-yl-propionic acid propyl ester 
• 107-08-4 1-iodo-propane 
• 591-87-7 Allyl acetate 

Downstream Products

• 591-87-7 Allyl acetate 

Relevant articles and documents

THIOPHENE-2-ALDEHYDE IN THE DARZENS REACTION

The reaction of the title compound with dichloroacetic acid esters in the presence of butyllithium gave esters of 3-thienyl-3-hydroxy-2,2-dichloropropionic acid. Keywords: dichloroacetate, dichlorohydrin.

Process for producing dichloroacetoxypropane and derivatives thereof

A process for producing dichloroacetoxypropane comprising reacting allyl acetate with chlorine in a gaseous phase in the presence of a catalyst. The dichloroacetoxypropane obtained may be converted to dichloropropanol and epichlorohydrin.

REACTIVITY OF CHLOROSUBSTITUTED α-EPOXIDES AND SYNTHESES UNDER THESE COMPOUNDS

The reactivity of chloroepoxyethanes in reactions with nucleophiles and electrophiles increases sharply with the accumulation of chlorine atoms on the epoxide ring.The reaction rate correlates with the nucleophile strength.Reactions with strong nucleophiles proceed through epoxide isomerization and lead to chloroacetic acid derivatives.Addition to the epoxide ring is found only for several weak nucleophiles.