37627-79-5

Basic information

• Product Name: N-[2-(3-methoxy-4-hydroxy-phenyl)ethyl]phthalimide
• Synonyms: N-[2-(3-methoxy-4-hydroxy-phenyl)ethyl]phthalimide
• CAS NO: 37627-79-5
• Molecular Weight: 297.31
• Mol File: 37627-79-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[2-(3-methoxy-4-hydroxy-phenyl)ethyl]phthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(3-methoxy-4-hydroxy-phenyl)ethyl]phthalimide(37627-79-5)
• EPA Substance Registry System: N-[2-(3-methoxy-4-hydroxy-phenyl)ethyl]phthalimide(37627-79-5)

Safety Data

• Hazardous Substances Data: 37627-79-5(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 554-52-9 3-Methoxytyramine 
• 75-52-5 nitromethane 
• 22509-74-6 N-ethoxycarbonylphthalimide 
• 121-33-5 vanillin 

Downstream Products

• 51-61-6 dopamine 
• 57894-18-5 2-[2-(3,4-dihydroxyphenyl)ethyl]-1,3-dioxoisoindoline 

Relevant articles and documents

Synthesis of condensed tetrahydroisoquinoline class of alkaloids by employing TfOH-mediated imide carbonyl activation

Isoquinoline-based polycyclic lactams such as isoindoloisoquinolinones, pyrroloisoquinolinones, and benzo[a]quinolizinones were successfully assembled from the corresponding imides by using a TfOH-mediated (TfOH = trifluoromethanesulfonic acid) imide carbonyl activation and cyclization strategy. By employing this simple method, the isoquinoline alkaloids crispine A, trolline/oleracein E, and erythrinarbine were successfully synthesized in racemic form. The reaction of unsymmetrical N-phenethylphthalimides with TfOH displayed excellent regioselectivity, which was rationalized by DFT calculations.

1-(4-Dimethylaminoethoxy-3-methoxyphenyl)-2-aminoalkanes.

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