37630-23-2

Basic information

• Product Name: Benzene, 1,2-dichloro-4-[(1E)-2-nitroethenyl]-
• CAS NO: 37630-23-2
• Molecular Formula: C8H5Cl2NO2
• Molecular Weight: 218.039
• Mol File: 37630-23-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzene, 1,2-dichloro-4-[(1E)-2-nitroethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,2-dichloro-4-[(1E)-2-nitroethenyl]-(37630-23-2)
• EPA Substance Registry System: Benzene, 1,2-dichloro-4-[(1E)-2-nitroethenyl]-(37630-23-2)

Safety Data

• Hazardous Substances Data: 37630-23-2(Hazardous Substances Data)

Upstream product

• 75-52-5 nitromethane 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 102-49-8 3,4-dichlorobenzyl amine 

Downstream Products

• 1228600-00-7 (1R,5R,6S,7R)-6-(3,4-dichlorophenyl)-1-hydroxy-7-nitrobicyclo[3.2.1]octan-8-one 
• 1384849-45-9 2-(2,2-dichloro-1-(3,4-dichlorophenyl)-2-nitroethyl)isoindoline-1,3-dione 
• 1420742-99-9 1-(tert-butoxyformamido)-2,2-dibromo-1-(3,4-dichlorophenyl)-2-nitroethane 
• 1459775-51-9 3-(3,4-dichloro-phenyl)quinolin-2(1H)-one 
• 1555971-81-7 (3-(3,4-dichlorophenyl)-5-phenyl-1H-pyrrol-2-yl)(phenyl)methanone 
• 92023-56-8 (1S,4R,5S,6R)-5-(3,4-Dichloro-phenyl)-6-nitro-bicyclo[2.2.1]hept-2-ene 
• 23211-38-3 (Z)-4-(2-bromo-2-nitrovinyl)-1,2-dichlorobenzene 
• 55446-64-5 1,2-Dichloro-4-(1,2-dibromo-2-nitro-ethyl)-benzene 
• 917473-16-6 4-(3,4-Dichloro-phenyl)-7-(1-isopropyl-piperidin-4-ylmethoxy)-1,2,3,4-tetrahydro-[2,6]naphthyridine 

Relevant articles and documents

Catalytic Asymmetric Construction of Tertiary Carbon Centers Featuring an α-Difluoromethyl Group with CF2H-CH2-NH2as the "building Block"

We report here for the first time a novel difluoromethylated ketimine building block condensed by thioisatin and difluoroethylamine, offering efficient access to a broad range of enantioenriched products bearing difluoroethylamine units (27 examples, ≤98% yield, >99% ee) in the presence of quinine-derived squaramide. Further transformation of the intermediate would generate a variety of versatile functional blocks like α-difluoromethyl amines, β-amino acid, and β-diamine with retention of the enantiomeric excess at the difluoromethyl-bound carbon.

Facile Synthesis of 1,3,5-Triarylbenzenes and 4-Aryl-NH-1,2,3-Triazoles Using Mesoporous Pd-MCM-41 as Reusable Catalyst

We report mesoporous nano-Pd-MCM-41 catalyzed rapid and efficient synthesis of 1,3,5-triarylbenzenes via de-nitrative cyclotrimerization of β-nitrostyrenes. All the reactions were very fast and high yielding. The Pd-MCM-41 was also very effective in catalyzing de-nitrative [3+2] cycloaddition of β-nitrostyrenes with TMSN3 to synthesize 4-aryl-NH-1,2,3-triazoles. The catalyst was reused at least up to eight times with minimum loss of catalytic activity.

Squaramide-Linked Chloramphenicol Base Hybrid Catalysts for the Asymmetric Michael Addition of 2,3-Dihydrobenzofuran-2-carboxylates to Nitroolefins

An array of hybrid catalysts incorporating a chloramphenicol base moiety linked to another chiral scaffold through a squaramide linker were developed and successfully used in the Michael addition of 2,3-dihydrobenzofuran-2-carboxylates to nitroolefins. Control experiments suggested that the hybrid catalysts were more reactive than nonhybridized bifunctional catalysts, and matching of the chirality between the two scaffolds was crucial for high reactivity and stereoselectivity. These hybrid organocatalysts could be used with a variety of substrates. At a 0.5 mol-% catalyst loading, a range of 2,3-dihydrobenzofuran-2-carboxylates derivatives bearing quaternary and tertiary stereogenic centers were obtained in high yields (up to 98 %) with excellent enantioselectivities (up to 99 % ee) and moderate diastereoselectivities (up to 8:92 dr).