376594-67-1 Usage
General Description
LY 450108 is a research chemical that is known for its potential application in the treatment of schizophrenia. It acts as a selective sigma receptor antagonist and has been shown to have antipsychotic and anti-amnesic properties in preclinical studies. Additionally, it has been found to have a low affinity for dopamine and serotonin receptors, which suggests it may have a unique mechanism of action compared to other antipsychotic drugs. LY 450108 has been the subject of various preclinical studies and shows promise as a potential therapeutic agent for treating schizophrenia and other psychiatric disorders, although further research is needed to fully understand its safety and efficacy in humans.
Check Digit Verification of cas no
The CAS Registry Mumber 376594-67-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,6,5,9 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 376594-67:
(8*3)+(7*7)+(6*6)+(5*5)+(4*9)+(3*4)+(2*6)+(1*7)=201
201 % 10 = 1
So 376594-67-1 is a valid CAS Registry Number.
376594-67-1Relevant articles and documents
Synthesis of 14C-labeled and tritiated AMPA potentiator LY450108
Czeskis, Boris A.,O'Bannon, Douglas D.,Wheeler, William J.,Clodfelter, Dean K.
, p. 85 - 100 (2007/10/03)
Asymmetric synthesis of AMPA potentiator LY450108-[14C] containing 14C-label attached to the chiral center of the molecule, was accomplished based on Evans' chiral oxazolidinone auxiliary method. Diastereoselective methylation of p-n
