377080-80-3Relevant articles and documents
Enantioselective synthesis of α,α-disubstituted amines from nitroalkenes
Leroux, Mary-Lorene,Le Gall, Thierry,Mioskowski, Charles
, p. 1817 - 1823 (2007/10/03)
Disubstituted nitroalkenes were converted into enantiomerically enriched amines (isolated as their hydrochloride salts) with enantiometric excesses of 88 to >95% in there steps: (a) highly stereoselective conjugate addition of the potassium salt of 4-phenyloxazolidin-2-one; (b) radical-mediated removal of the nitro group; (c) cleavage of the oxazolidinone.