378185-89-8

Basic information

• Product Name: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6-dimethyl-
• CAS NO: 378185-89-8
• Molecular Formula: C15H24O2Si
• Molecular Weight: 264.44
• Mol File: 378185-89-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6-dimethyl-(378185-89-8)
• EPA Substance Registry System: Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6-dimethyl-(378185-89-8)

Safety Data

• Hazardous Substances Data: 378185-89-8(Hazardous Substances Data)

Upstream product

• 80826-86-4 4-iodo-3,5-dimethylphenol 
• 70547-87-4 2,6-dimethyl-4-hydroxybenzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 108-68-9 3,5-Dimethylphenol 
• 7463-51-6 4-bromo-3,5-dimethylphenol 
• 68-12-2 N,N-dimethyl-formamide 
• 149228-92-2 (4-bromo-3,5-dimethylphenoxy)(tert-butyl)-di-methylsilane 
• 378185-88-7 tert-butyl(4-iodo-3,5-dimethylphenoxy)dimethylsilane 

Downstream Products

• 70547-87-4 2,6-dimethyl-4-hydroxybenzaldehyde 
• 378185-91-2 4-(Bromomethyl)-3,5-dimethyl-tert-butyldimethylsilyloxyphenol 
• 378185-97-8 (2R)-1-[(4R)-4-Benzyl-2-oxo-1,3-oxazolan-3-yl]-3-(4-tert-butyldimethylsilyloxy-2,6-dimethylphenyl)-2-phenylpropan-1-one 
• 378185-93-4 (2R)-1-[(4R)-4-Benzyl-2-oxo-1,3-oxazolan-3-yl]-2-cyclohexyl-3-(4-tert-butyldimethylsilyloxy-2,6-dimethylphenyl)propan-1-one 
• 75056-97-2 2,6-dimethyl-4-hydroxybenzoic acid 
• 95741-45-0 4-(benzyloxy)-2,6-dimethylbenzoic acid 
• 28924-92-7 4-(benzyloxy)-2,6-dimethylbenzaldehyde 
• 1021166-08-4 4-formyl-3,5-dimethylphenyl trifluoromethanesulfonate 
• 378185-90-1 (4-tert-Butyldimethylsilyloxy-2,6-dimethylphenyl)methanol 

Relevant articles and documents

NOVEL COMPOUNDS AND THEIR USES AS THYROID HORMONE RECEPTOR AGONISTS

A compound of formula (I) or (Ia), or a tautomer or a pharmaceutically acceptable salt thereof is provided. Compounds of formula (II) to (V), or a tautomer or a pharmaceutically acceptable salt thereof are also provided. These compounds and the pharmaceutical compositions containing them are useful for the treatment of diseases such as obesity, hyperlipidemia, hypercholesterolemia and diabetes and other related disorders and diseases, and may be useful for other diseases such as NASH, atherosclerosis, cardiovascular diseases, hypothyroidism, thyroid cancer and other disorders and diseases related thereto． (I), (Ia)

Enantioselective Construction of Functionalized Tetrahydrocarbazoles Enabled by Asymmetric Relay Catalysis of Gold Complex and Chiral Br?nsted Acid

An intramolecular hydroamination/Michael addition cascade is realized using a combination of gold(I) complex and chiral BINOL-phosphoric acid, affording fused-tetrahydrocarbazole scaffolds in excellent yields and high enantioselectivities.

Stereospecific syntheses of 2-alkyl and 2-phenyl substituted 3-(2,6-dimethyl-4-hydroxyphenyl)propanoic acids

Stereospecific syntheses of 2-methyl-, 2-ethyl-, 2-cyclohexyland 2-phenyl- substituted 3-(2,6-dimethyl-4-hydroxyphenyl)propanoic acids were developed. The key steps for the formation of the stereogenic centers involved the utilization of Evans' 4-benzyl-2-oxazolidinone chiral auxiliary. These compounds were designed to replace the N-terminal tyrosine residue in opioid peptides.