37856-18-1

Basic information

• Product Name: 4(3H)-Quinazolinone, 3-(2-methoxyphenyl)-2-phenyl-
• CAS NO: 37856-18-1
• Molecular Formula: C21H16N2O2
• Molecular Weight: 328.37
• Mol File: 37856-18-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(3H)-Quinazolinone, 3-(2-methoxyphenyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(3H)-Quinazolinone, 3-(2-methoxyphenyl)-2-phenyl-(37856-18-1)
• EPA Substance Registry System: 4(3H)-Quinazolinone, 3-(2-methoxyphenyl)-2-phenyl-(37856-18-1)

Safety Data

• Hazardous Substances Data: 37856-18-1(Hazardous Substances Data)

Upstream product

• 59386-96-8 N-(2-methoxyphenyl)benzimidoyl chloride 
• 134-20-3 2-carbomethoxyaniline 
• 611-73-4 Benzoylformic acid 
• 70083-21-5 2-amino-N-(2-methoxyphenyl)benzamide 
• 5395-00-6 N-(2-methoxyphenyl)benzamide 
• 552-16-9 ortho-nitrobenzoic acid 
• 854829-04-2 N-benzoyl-N-(2-nitro-benzoyl)-o-anisidine 

Relevant articles and documents

α-Keto Acids as Triggers and Partners for the Synthesis of Quinazolinones, Quinoxalinones, Benzooxazinones, and Benzothiazoles in Water

A general and efficient method for the synthesis of quinazolinones, quinoxalinones, benzooxazinones, and benzothiazoles from the reactions of α-keto acids with 2-aminobenzamides, benzene-1,2-diamines, 2-aminophenols, and 2-aminobenzenethiols, respectively, is described. The reactions were conducted under catalyst-free conditions, using water as the sole solvent with no additive required, and successfully applied to the synthesis of sildenafil. More importantly, these reactions can be conducted on a mass scale, and the products can be easily purified through filtration and washing with ethanol (or crystallized).