37901-92-1

Basic information

• Product Name: 4-(acetylamino)-3-methylbenzoic acid
• Synonyms: 4-(acetylamino)-3-methylbenzoic acid;AKOS BBV-013836;UKRORGSYN-BB BBV-013836;4-(acetylamino)-3-methylbenzoic acid(SALTDATA: FREE);4-Acetamido-3-methylbenzoic acid
• CAS NO: 37901-92-1
• Molecular Formula: C₁₀H₁₁NO₃
• Molecular Weight: 193.1992
• Mol File: 37901-92-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 114-116 °C
• Boiling Point: 411°Cat760mmHg
• Flash Point: 202.4°C
• Appearance: /
• Density: 1.276g/cm³
• Vapor Pressure: 1.72E-07mmHg at 25°C
• Refractive Index: 1.607
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.34±0.10(Predicted)
• CAS DataBase Reference: 4-(acetylamino)-3-methylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(acetylamino)-3-methylbenzoic acid(37901-92-1)
• EPA Substance Registry System: 4-(acetylamino)-3-methylbenzoic acid(37901-92-1)

Safety Data

• Hazardous Substances Data: 37901-92-1(Hazardous Substances Data)

Usage

General Description

4-(acetylamino)-3-methylbenzoic acid is a chemical compound with the molecular formula C11H11NO3. It is a derivative of benzoic acid, containing a methyl group and an acetylamino group attached to the benzene ring. 4-(acetylamino)-3-methylbenzoic acid is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various drugs and pharmaceuticals. It has potential anti-inflammatory and analgesic properties, making it useful for the treatment of pain and inflammation-related conditions. Its structure and properties make it an important building block for the production of various pharmaceutical compounds.

InChI:InChI=1/C10H11NO3/c1-6-5-8(10(13)14)3-4-9(6)11-7(2)12/h3-5H,1-2H3,(H,11,12)(H,13,14)

Upstream product

• 2050-43-3 N-(2,4-dimethylphenyl)acetamide 
• 2486-70-6 4-amino 3-methylbenzoic acid 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 

Downstream Products

• 37901-93-2 4-acetamido-3-methyl-5-nitrobenzoic acid 
• 808745-06-4 ethyl 4-acetamido-3-methyl-5-nitrobenzoate 
• 856839-94-6 ethyl 3,4-diamino-5-methylbenzoate 
• 808745-05-3 ethyl 4-acetamido-3-methylbenzoate 
• 1263818-07-0 methyl 4-acetamido-3-methyl-5-nitrobenzoate 
• 668276-44-6 methyl 4-amino-3-methyl-5-nitrobenzoate 
• 668276-43-5 methyl 3,4-diamino-5-methylbenzoate 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR

Disclosed are heterocyclic compounds as inhibitors of FGFR-4 represented by formula (I). Also disclosed is a pharmaceutical composition that includes an inhibitor of FGFR-4. The compounds maybe used to treat diseases mediated with abnormality of FGFR-4 and /or FGF19, such as hepatocellular carcinoma and other forms of cancer.

AMIDE-SUBSTITUTED IMIDAZO COMPOUNDS AS SELECTIVE INHIBITORS OF INDOLEAMINE 2, 3-DIOXYGENASES

Disclosed herein are amide-substituted imidazo compounds and pharmaceutical compositions comprising at least one such novel benzoimidazoles, processes for the preparation thereof, and the method for using the same in therapy. In particular, disclosed herein are certain amide-substituted imidazo compounds that are useful for inhibiting indoleamine 2, 3-dioxygenase and for treating diseases or disorders mediated thereby.

Calcitonin gene related peptide receptor antagonists

The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.