37965-26-7

Basic information

• Product Name: 2,6-dimethyl-4-triphenylsilanyl-pyridine
• Synonyms: 2,6-dimethyl-4-triphenylsilanyl-pyridine
• CAS NO: 37965-26-7
• Molecular Weight: 365.55
• Mol File: 37965-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-dimethyl-4-triphenylsilanyl-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-4-triphenylsilanyl-pyridine(37965-26-7)
• EPA Substance Registry System: 2,6-dimethyl-4-triphenylsilanyl-pyridine(37965-26-7)

Safety Data

• Hazardous Substances Data: 37965-26-7(Hazardous Substances Data)

Upstream product

• 87117-15-5 1-methoxy-2,6-dimethylpyridinium methyl sulfate 
• 789-25-3 HSiPh₃ 

Relevant articles and documents

Photochemical C-H Silylation and Hydroxymethylation of Pyridines and Related Structures: Synthetic Scope and Mechanisms

Considering the synthetic relevance of heteroarenes in various areas ranging from organic synthesis to medicinal chemistry, developing practically simple methodologies to access functionalized heteroarenes is of a significant value. Described herein is an efficient approach for C-H silylation and hydroxymethylation of pyridines and related heterocycles by the combination of silanes or methanol with readily available N-methoxypyridinium ions with a low catalyst loading (2 mol %) under blue light irradiation. The synthetic importance of the developed reactions is demonstrated by the synthesis of biologically relevant compounds. Electron paramagnetic resonance spectroscopy, quantum yield measurements, and density-functional theory calculations allowed us to understand reaction mechanisms of both photocatalytic reactions.