3800-86-0

Basic information

• Product Name: DEXAMETHASONE HEMISUCCINATE
• Synonyms: DEXAMETHASONE HEMISUCCINATE;DEXAMETHASONE HEMISUCCINATE : BSA;1,4-PREGNADIEN-9ALPHA-FLUORO-16ALPHA-METHYL-11BETA, 17ALPHA, 21-TRIOL 3,20-DIONE 21-HEMISUCCINATE;1,4-PREGNADIEN-9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE;1,4-PREGNADIEN-9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE : BSA;(11beta,16alpha)-21-(3-Carboxy-1-oxopropoxy)-9-fluoro-11,17-dihydroxy- 16-methylpregna-1,4-diene-3,20-dione
• CAS NO: 3800-86-0
• Molecular Formula: C₂₆H₃₃FO₈
• Molecular Weight: 492.53
• Mol File: 3800-86-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 686 ºC at 760 mmHg
• Flash Point: 368.7 ºC
• Appearance: /
• Density: 1.36 g/cm³
• Vapor Pressure: 8.72E-22mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
• CAS DataBase Reference: DEXAMETHASONE HEMISUCCINATE(CAS DataBase Reference)
• NIST Chemistry Reference: DEXAMETHASONE HEMISUCCINATE(3800-86-0)
• EPA Substance Registry System: DEXAMETHASONE HEMISUCCINATE(3800-86-0)

Safety Data

• Hazardous Substances Data: 3800-86-0(Hazardous Substances Data)

Usage

Description

DEXAMETHASONE HEMISUCCINATE is a glucocorticoid derivative of Dexamethasone, characterized by its anti-inflammatory properties. It plays a crucial role in regulating T cell survival, growth, and differentiation, while also inhibiting the induction of nitric oxide synthase.

Uses

Used in Pharmaceutical Industry:
DEXAMETHASONE HEMISUCCINATE is used as an anti-inflammatory agent for its ability to regulate T cell survival, growth, and differentiation. It is particularly effective in managing inflammation and modulating the immune response.
Used in Immunomodulation:
DEXAMETHASONE HEMISUCCINATE is used as an immunomodulator to inhibit the induction of nitric oxide synthase, which can help in controlling the immune system's response and reducing inflammation.
Used in Treatment of Inflammatory Conditions:
DEXAMETHASONE HEMISUCCINATE is used as a therapeutic agent for treating various inflammatory conditions, leveraging its anti-inflammatory and immunomodulatory properties to alleviate symptoms and improve patient outcomes.

InChI:InChI=1/C26H33FO8/c1-14-10-18-17-5-4-15-11-16(28)8-9-23(15,2)25(17,27)19(29)12-24(18,3)26(14,34)20(30)13-35-22(33)7-6-21(31)32/h8-9,11,14,17-19,29,34H,4-7,10,12-13H2,1-3H3,(H,31,32)/t14-,17+,18+,19+,23+,24+,25+,26+/m1/s1