38009-92-6

Basic information

• Product Name: Ethanone, 2-chloro-1-phenyl-2-(phenylsulfonyl)-
• CAS NO: 38009-92-6
• Molecular Formula: C14H11ClO3S
• Molecular Weight: 294.759
• Mol File: 38009-92-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-chloro-1-phenyl-2-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-chloro-1-phenyl-2-(phenylsulfonyl)-(38009-92-6)
• EPA Substance Registry System: Ethanone, 2-chloro-1-phenyl-2-(phenylsulfonyl)-(38009-92-6)

Safety Data

• Hazardous Substances Data: 38009-92-6(Hazardous Substances Data)

Upstream product

• 93-58-3 benzoic acid methyl ester 
• 7205-98-3 chloromethyl phenyl sulfone 
• 28322-50-1 2-diazo-1-phenyl-2-(phenylsulfonyl)ethan-1-one 
• 70-11-1 α-bromoacetophenone 
• 873-55-2 sodium benzenesulfonate 
• 16222-10-9 1-phenyl-2-(phenylthio)ethanone 
• 38042-52-3 2-chloro-2-(phenylsulfinyl)-1-phenyl-1-ethanone 
• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 861524-26-7 2-benzenesulfonyl-2,2-dichloro-1-phenyl-ethanone 
• 64-17-5 ethanol 

Downstream Products

• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 40230-56-6 2-chloro-1-phenyl-2-(phenylsulfonyl)ethan-1-ol 
• 195371-23-4 p-Tolyl-chlorbrommethyl-sulfon 
• 861524-26-7 2-benzenesulfonyl-2,2-dichloro-1-phenyl-ethanone 
• 7205-98-3 chloromethyl phenyl sulfone 
• 925901-22-0 2-benzenesulfonyl-2-bromo-2-chloro-1-phenyl-ethanone 
• 77006-49-6 2-Benzenesulfonyl-3-phenyl-5,6-dihydro-imidazo[2,1-b]thiazole 

Relevant articles and documents

Copper Triflate Mediated α-Monohalogenation of α-Diazo β-Ketosulfones with Ammonium Halides

Copper triflate mediated α-monohalogenation of α-diazo β-ketosulfones with ammonium halides provides the corresponding α-halo β-ketosulfones. Different metal triflates are investigated for this facile and efficient transformation. A plausible mechanism is proposed.

Chemoselective mono halogenation of β-keto-sulfones using potassium halide and hydrogen peroxide; synthesis of halomethyl sulfones and dihalomethyl sulfones

The synthesis of α-halo β-keto-sulfones using potassium halide and hydrogen peroxide as a chemoselective mono halogenation reagent and the synthesis of α,α-symmetrical and asymmetrical dihalo β-keto-sulfones and α-halo, α-alkyl and β-keto-sulfones is described. Base induced cleavage of α-halo β-keto-sulfones, α,α-dihalo β-keto-sulfones, and α-halo, α-alkyl β-keto-sulfones afforded the corresponding halomethyl sulfones, dihalomethyl sulfones and haloalkyl sulfones.

Effect of Structural Change on Acute Toxicity and Antiinflammatory Activity in a Series of Imidazothiazoles and Thiazolobenzimidazoles

The effect of structural change on the biological activity of a series of imidazothiazoles and thiazolobenzimidazoles is described.It was found that compounds with polar substituents at the 2 or 3 position of the ring system are less acutely toxic while maintaining antiinflammatory activity.Other structural changes, such as the incorporation of a gem-dimethyl substituent in the 6 position, increase acute toxicity and eliminate antiinflammatory activity.The compound with the best activity/toxicity ratio contains an alkyl sulfonyl substituent on the thiazole ring.The thiazolobenzimidazole analogues are more potent than the imidazole analogues.