380237-44-5

Basic information

• Product Name: Carbamic acid, [2-[[[4-[[(acetyloxy)amino]iminomethyl]phenyl]methyl]amino]-2-oxoethyl]-, 1,1-dimethylethyl ester
• CAS NO: 380237-44-5
• Molecular Formula: C17H24N4O5
• Molecular Weight: 364.401
• Mol File: 380237-44-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-[[[4-[[(acetyloxy)amino]iminomethyl]phenyl]methyl]amino]-2-oxoethyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-[[[4-[[(acetyloxy)amino]iminomethyl]phenyl]methyl]amino]-2-oxoethyl]-, 1,1-dimethylethyl ester(380237-44-5)
• EPA Substance Registry System: Carbamic acid, [2-[[[4-[[(acetyloxy)amino]iminomethyl]phenyl]methyl]amino]-2-oxoethyl]-, 1,1-dimethylethyl ester(380237-44-5)

Safety Data

• Hazardous Substances Data: 380237-44-5(Hazardous Substances Data)

Upstream product

• 4530-20-5 BOC-glycine 
• 600707-97-9 C₁₀H₁₃N₃O₂ 
• 66389-80-8 tert-butyl N-[(4-cyanophenyl)methyl]carbamate 
• 380237-42-3 C₁₅H₂₁N₃O₄ 
• 220648-78-2 tert-butyl-(4-(N’-hydroxycarbamimidoyl)benzyl)carbamate 
• 10406-25-4 4-aminobenzyl cyanide 

Downstream Products

• 600141-81-9 H-Gly-4-(Acetyloxamidino)benzylamide×HCl 

Relevant articles and documents

4-Amidinobenzylamine-Based Inhibitors of Urokinase

A series of 4-amidinobenzylamine-based peptidomimetic inhibitors of urokinase was synthesized. The most potent one, benzylsulfonyl-D-Ser-Ala-4-amidinobenzylamide 16, inhibits uPA with a Ki of 7.7 nM but is less selective than 10 with a Gly as P2 residue. Hydroxyamidine and carbonate prodrugs were prepared, which are rapidly converted into the active inhibitors in rats after subcutaneous application.