380383-84-6

Basic information

• Product Name: Hydrazinecarboxylic acid, 1-(3-cyanophenyl)-, 1,1-dimethylethyl ester
• CAS NO: 380383-84-6
• Molecular Formula: C12H15N3O2
• Molecular Weight: 233.27
• Mol File: 380383-84-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Hydrazinecarboxylic acid, 1-(3-cyanophenyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarboxylic acid, 1-(3-cyanophenyl)-, 1,1-dimethylethyl ester(380383-84-6)
• EPA Substance Registry System: Hydrazinecarboxylic acid, 1-(3-cyanophenyl)-, 1,1-dimethylethyl ester(380383-84-6)

Safety Data

• Hazardous Substances Data: 380383-84-6(Hazardous Substances Data)

Upstream product

• 870-46-2 t-butoxycarbonylhydrazine 
• 69113-59-3 3-iodobenzonitrile 

Downstream Products

• 401949-25-5 tert-Butyl 2-(3-cyanophenyl)-3-(2,2,2-trifluoroacetyl)carbazate 

Relevant articles and documents

Synthesis of N-aryl hydrazides by copper-catalyzed coupling of hydrazides with aryl iodides.

[reaction--see text] A convenient method for intermolecular N-arylation of hydrazides with substituted aryl iodides in the presence of a copper catalyst and Cs(2)CO(3) is reported. The C-N coupling of N-Boc hydrazine with para- and meta-substituted aryl iodides afforded the N-arylated products A, regioselectively. A reversal in regioselectivity is observed for the arylation of benzoic hydrazide with ortho-substituted aryl iodides, providing the N'-arylated products B.

Aza-amino acid derivatives (factor Xa inhibitors 15)

The invention relates to semicarbazides of the general formula I where R1, R2, R3, R4 and I have the meaning indicated in claim 1. The compounds of the formula I can be employed as pharmaceutical active compound