38047-66-4

Basic information

• Product Name: Piperidine, 2,6-diphenyl-, cis-
• CAS NO: 38047-66-4
• Molecular Formula: C17H19N
• Molecular Weight: 237.345
• Mol File: 38047-66-4.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Piperidine, 2,6-diphenyl-, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 2,6-diphenyl-, cis-(38047-66-4)
• EPA Substance Registry System: Piperidine, 2,6-diphenyl-, cis-(38047-66-4)

Safety Data

• Hazardous Substances Data: 38047-66-4(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 3466-80-6 2-phenylpiperidine 
• 591-51-5 phenyllithium 
• 3558-69-8 2,6-diphenylpyridine 
• 100-52-7 benzaldehyde 
• 134848-31-0 N-Nitroso-cis-2,6-diphenylpiperidine 
• 22188-04-1 (2S,6R)-1-Nitroso-2,6-diphenyl-piperidin-4-one 
• 1304540-02-0 (-)-tert-butyl methoxy[(1S)-1-phenylprop-2-en-1-yl]carbamate 
• 1569095-83-5 (6S)-1-methoxy-6-phenyl-piperidin-2-one 
• 1569095-81-3 (6S)-1-methoxy-6-phenyl-3,6-dihydropyridin-2(1H)-one 
• 1569095-72-2 N-methoxy-N-[(1S)-1-phenylprop-2-en-1-yl]but-3-enamide 
• 87802-71-9 (E)-methyl cinnamyl carbonate 
• 439587-54-9 N-tert-butoxycarbonyl-(R)-1-phenylbut-3-enamine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 7433-53-6 cis-1,2-diphenylcylopentane 
• 7433-54-7 1,5-diphenyl-1-pentene 
• 36149-53-8 1-amino-2r,6c-diphenyl-piperidine 
• 102747-57-9 1-benzylidenamino-2r,6c-diphenyl-piperidine 
• 36149-53-8 (+/-)-1-amino-2r,6t-diphenyl-piperidine 
• 102747-57-9 (+/-)-1-benzylidenamino-2r,6t-diphenyl-piperidine 
• 38047-68-6 2,6-Diphenyl-2,3,4,5-tetrahydropyridin 
• 88365-67-7 1-Chlor-cis-2,6-diphenylpiperidin 
• 86926-24-1 meso-N-methyl-2.6-diphenylpiperidine 
• 67787-59-1 (+/-)-1-nitroso-2r,6t-diphenyl-piperidine 
• 134848-31-0 N-Nitroso-cis-2,6-diphenylpiperidine 

Relevant articles and documents

Borane-Catalyzed Reduction of Pyridines via a Hydroboration/Hydrogenation Cascade

We have developed a method for a B(C6F5)3-catalyzed hydroboration/hydrogenation cascade reduction of pyridines. The method was particularly effective for 2,3-disubstituted pyridines, which generated piperidines in high yields with high cis selectivity. Mechanistic studies indicated that the pyridine substrates and the piperidine products sequentially acted as bases in cooperation with B(C6F5)3to split H2. The broad functional group tolerance of the method allowed its use for the synthesis of some biologically active molecules.

B(C6F5)3-Catalyzed Cascade Reduction of Pyridines

B(C6F5)3 has been found to be an effective catalyst for reduction of pyridines and other electron-deficient N-heteroarenes with hydrosilanes (or hydroboranes) and amines as the reducing reagents. The success of this development hinges upon the realization of a cascade process of dearomative hydrosilylation (or hydroboration) and transfer hydrogenation. The broad functional-group tolerance (e.g. ketone, ester, unactivated olefins, nitro, nitrile, heterocycles, etc.) implies high practical utility.

Facile denitrosation of Cyclic N-nitrosamines with hydrazoic acid

A simple and facile method for the denitrosation of cyclic N-nitrosamines using HN3 (concentrated H2SO4+NaN3) is reported. In this method, limited usage of this reagent does not affect the carbonyl group.