38049-04-6

Basic information

• Product Name: DEHYDROXYMENTHOFUROLACTONE
• Synonyms: DEHYDROXYMENTHOFUROLACTONE;(6R)-3,6β-Dimethyl-4,5,6,7-tetrahydrobenzofuran-2(7aαH)-one;(6R)-3,6β-Dimethyl-5,6,7,7aα-tetrahydrobenzofuran-2(4H)-one;(6R)-5,6,7,7aα-Tetrahydro-3,6-dimethylbenzofuran-2(4H)-one;5,6,7,7aα-Tetrahydro-3,6β-dimethylbenzofuran-2(4H)-one
• CAS NO: 38049-04-6
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• Mol File: 38049-04-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 303.7±11.0 °C(Predicted)
• Appearance: /
• Density: 1.07±0.1 g/cm3(Predicted)
• CAS DataBase Reference: DEHYDROXYMENTHOFUROLACTONE(CAS DataBase Reference)
• NIST Chemistry Reference: DEHYDROXYMENTHOFUROLACTONE(38049-04-6)
• EPA Substance Registry System: DEHYDROXYMENTHOFUROLACTONE(38049-04-6)

Safety Data

• Hazardous Substances Data: 38049-04-6(Hazardous Substances Data)

Upstream product

• 132060-11-8 2-(4-Methyl-7-oxa-bicyclo[4.1.0]hept-1-yl)-propionic acid methyl ester 
• 143837-01-8 2-(1,2-Dihydroxy-4-methyl-cyclohexyl)-propionic acid ethyl ester 
• 96562-29-7 p-menth-3-en-9-oic acid 
• 2570-63-0 thallium(III) acetate 
• 159561-57-6 p-menth-3-en-9-oic acid ethyl ester 
• 589-92-4 1-methylcyclohexan-4-one 
• 54263-85-3 (4-methyl-cyclohexyliden)-acetic acid methyl ester 
• 31538-47-3 2-(4-Methyl-cyclohex-1-enyl)-propionic acid methyl ester 
• 1334384-66-5 dimethyl 2-(4-methylcyclohexylidene)succinate 
• 38049-03-5 (+/-)-6-methyl-3-methylene-hexahydrobenzofuran-2(3H)-one 
• 106-25-2 Nerol 
• 106-24-1 Geraniol 
• 2565-83-5 geraniol methyl ether 
• 141-12-8 neryl acetate 

Downstream Products

• 494-90-6 menthofuran 
• 676248-66-1 (1R,4S,8S)-3-oxo-p-menthan-9-oic acid 
• 120442-21-9 (1R,4S,8R)-3-oxo-p-menthan-9-oic acid 
• 676248-65-0 (1R,4R,8S)-3-oxo-p-menthan-9-oic acid 
• 75714-56-6 (1R,8R)-3-oxo-cis-p-menthan-9-oic acid 
• 17957-94-7 (+)-menthofuran 
• 13834-08-7 <1R>-5(R)-methyl-2(S)-<1(S)-methyl-2-hydroxyethyl>cyclohexanol 
• 13834-23-6 (1R,3S,4R,8S)-3,9-p-menthanediol 
• 289634-71-5 (1R,3R,4R,8S)-3,9-p-menthanediol 
• 289634-70-4 (1R,4R,8S)-3-oxo-9-p-menthanyl acetate 
• 289634-69-1 (1R,3R,4R,8S)-3-hydroxy-9-p-menthanyl acetate 
• 13341-72-5 (+/-)-3,6-dimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one 

Relevant articles and documents

Regio- and stereoselective selenium dioxide allylic oxidation of (E)-dialkyl alkylidenesuccinates to (Z)-allylic alcohols: Synthesis of natural and unnatural butenolides

The first SeO2 induced (Z)-selective allylic alcohol formation of dialkyl alkylidenesuccinates has been demonstrated to accomplish one-step syntheses of several essential butenolides and fused butenolides via an unusual E- to Z- carbon-carbon d

An Efficient Entry Into Butenolides: Synthesis Of (+/-) Mintlactone

Osmylation of β,γ-unsaturated esters and acid catalysed cyclisation of the resultant diols generate butenolides in high yields.

Chemical Tranformation of Terpenoids. V. Acidic Conversions of 10-Hydroxygeraniol and 10-Hydroxynerol Derivatives Leading to Cyclic Monoterpenoids

Acid treatment of 1-O-acetyl-10-hydroxygeraniol (5a), 1-O-methyl-10-hydroxygeraniol (5b), 1-O-acetyl-10-hydroxynerol (6a), and 1-O-methyl-10-hydroxynerol (6b) was investigated under various conditions.It was found that treatment of 5a and 6a with HCOOH gave menth-1-ene-8,9-diol (7), while treatment of 5a, 5b, 6a, or 6b with BF3-etherate in CH2Cl2 furnished two menthofuran-type compounds (9, 10) and two bicyclooct-2-ene derivatives (17, 24).Both 9 and 10 were successfully converted to menthofuran (16) and 17 was converted to a bicyclooctenone derivative (23) which was a key intermediate for a synthesis of juvabione (27).Keywords - geraniol; nerol; 10-hydroxygeraniol; 10-hydroxynerol; 10-hydroxygeraniol derivative; 10-hydroxynerol derivative; uroterpenol; menthofuran; bicyclooct-2-ene derivative