380500-76-5

Basic information

• Product Name: [3-(tert-butyl-diphenyl-silanyloxy)-phenyl]-acetic acid ethyl ester
• CAS NO: 380500-76-5
• Molecular Weight: 418.608
• Mol File: 380500-76-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [3-(tert-butyl-diphenyl-silanyloxy)-phenyl]-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(tert-butyl-diphenyl-silanyloxy)-phenyl]-acetic acid ethyl ester(380500-76-5)
• EPA Substance Registry System: [3-(tert-butyl-diphenyl-silanyloxy)-phenyl]-acetic acid ethyl ester(380500-76-5)

Safety Data

• Hazardous Substances Data: 380500-76-5(Hazardous Substances Data)

Upstream product

• 621-37-4 m-hydroxyphenylacetic acid 
• 22446-38-4 ethyl 3-hydroxyphenylacetate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 380500-79-8 ethyl (5-tert-butoxycarbonyloxy-2-acetylphenyl)acetate 
• 380500-78-7 (2-acetyl-5-hydroxy-phenyl)-acetic acid ethyl ester 
• 380500-77-6 [2-acetyl-5-(tert-butyl-diphenyl-silanyloxy)-phenyl]-acetic acid ethyl ester 

Relevant articles and documents

A novel tandem [2 + 2] cycloaddition-Dieckmann condensation with ynolate anions. Efficient synthesis of substituted cycloalkenones and naphthalenes via formal [n + 1] cycloaddition

A novel tandem [2 + 2] cycloaddition-Dieckmann condensation via ynolate anions is described. Ynolate anions are useful for the formation of reactive β-lactone enolates via a pathway not involving the enolization of the corresponding β-lactones. The [2 + 2] cycloaddition of ynolate anions with δ- or σ-keto esters, followed by Dieckmann condensation, gives bicyclic β-lactones, which are easily decarboxylated to produce synthetically useful 2,3-disubstituted cyclopentenones and cyclohexenones in one pot. This tandem reaction was applied to a novel, one-pot synthesis of highly substituted naphthalenes.