3807-77-0

Basic information

• Product Name: 3-NITROACENAPHTHENE
• Synonyms: Acenaphthene, 3-nitro-
• CAS NO: 3807-77-0
• Molecular Formula: C₁₂H₉NO₂
• Molecular Weight: 0
• Product Categories: Naphthalene derivatives
• Mol File: 3807-77-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 389.8°Cat760mmHg
• Flash Point: 200.3°C
• Appearance: /
• Density: 1.357g/cm³
• Vapor Pressure: 6.22E-06mmHg at 25°C
• Refractive Index: 1.723
• CAS DataBase Reference: 3-NITROACENAPHTHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-NITROACENAPHTHENE(3807-77-0)
• EPA Substance Registry System: 3-NITROACENAPHTHENE(3807-77-0)

Safety Data

• Hazardous Substances Data: 3807-77-0(Hazardous Substances Data)

Usage

Description

3-Nitroacenaphthene is a chemical compound that is an impurity found in Acenaphthene, a polycyclic aromatic hydrocarbon known for its carcinogenic properties.

Uses

Used in Chemical Research:
3-Nitroacenaphthene is used as a research compound for studying the properties and reactions of polycyclic aromatic hydrocarbons and their derivatives. Its presence as an impurity in Acenaphthene makes it a subject of interest for understanding the potential health risks and environmental impact associated with exposure to these compounds.
Used in Environmental Monitoring:
3-Nitroacenaphthene can be used as an indicator for the presence of Acenaphthene and other polycyclic aromatic hydrocarbons in environmental samples. Monitoring the levels of 3-Nitroacenaphthene and related compounds can help assess the extent of pollution and implement appropriate measures to mitigate exposure and contamination.
Used in Industrial Processes:
3-Nitroacenaphthene may be used in the development and optimization of industrial processes that involve the production or handling of Acenaphthene and other polycyclic aromatic hydrocarbons. Understanding the presence and behavior of impurities like 3-Nitroacenaphthene can help improve safety measures, reduce waste, and enhance the overall efficiency of these processes.

InChI:InChI=1/C12H9NO2/c14-13(15)11-7-5-9-3-1-2-8-4-6-10(11)12(8)9/h1-3,5,7H,4,6H2

Upstream product

• 83-32-9 acenaphthene 
• 7697-37-2 nitric acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 3807-76-9 3,6-dinitroacenaphthene 
• 35338-47-7 3,8-dinitro-acenaphthene 
• 42101-93-9 2-nitro-naphthalene-1,8-dicarboxylic acid 
• 10353-98-7 3-Nitroacenaphthylen 
• 55939-13-4 1,2-dihydro-acenaphthylene-3-amine 
• 5209-31-4 3-bromoacenaphthene 
• 865758-20-9 3-phenyl-acenaphthylene 

Relevant articles and documents

Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides

A series of arylnaphthalimides were designed and synthesized to overcome the dose-limiting cytotoxicity of N-acetylated metabolites arising from amonafide, the prototypical antitumour naphthalimide whose biomedical properties have been related to its ability to intercalate the DNA and poison the enzyme Topoisomerase II. Thus, these arylnaphthalimides were first evaluated for their antiproliferative activity against two tumour cell lines and for their antitopoisomerase II in vitro activities, together with their ability to intercalate the DNA in vitro and also through docking modelization. Then, the well-known DNA damage response in Saccharomyces cerevisiae was employed to critically evaluate whether these novel compounds can damage the DNA in vivo. By performing all these assays we conclude that the 5-arylsubstituted naphthalimides not only keep but also improve amonafide's biological activities.